Crigler-Najjar Syndrome (CNS) is un conjugated hyperbilirubinemia caused by mutations in bilirubin UDP-glucuronosyl transferase (UGT1A1) gene which can transform the un conjugated bilirubin by conjugating it with glucuronic acid. There are two types of CNS.CNS-I is fatal because of the bilirubin encephalopathy combined with severe un conjugated hyperbilirubinaemia, while CNS-II is a moderate fo...

The cardinal symptom of acute encephalopathy is impairment consciousness onset during the course an infectious disease, with duration and severity meeting defined criteria. Acute consists multiple syndromes such as necrotizing encephalopathy, biphasic seizures late reduced diffusion clinically mild encephalitis/encephalopathy reversible splenial lesion. Among these syndromes, there are both sim...

The authors present the case of a newborn of an Rh-factorsensitized mother, who received early hospital discharge while icteric only to be readmitted at an Emergency Service at five days of age with signs of kernicterus. Despite treatment given, the neonate progressed with a clinical picture of bilirubin encephalopathy. The lack of interaction between the obstetric and neonatal teams, premature...

to evaluate the changes of abr values in hyperbilirubinemic newborns, 85 cases with severe jaundice (total bilirubin levels over 16 mg/dl and direct bilirubin less than 2 mg/dl) were selected from those admitted to children's medical center by simple sampling method. these infants had no other problem except jaundice. abr was taken before treatment in all cases and in some (10 cases) after...

To evaluate the changes of ABR values in hyperbilirubinemic newborns, 85 cases with severe jaundice (total bilirubin levels over 16 mg/dL and direct bilirubin less than 2 mg/dL) were selected from those admitted to Children's Medical Center by simple sampling method. These infants had no other problem except jaundice. ABR was taken before treatment in all cases and in some (10 cases) after...

OBJECTIVE To describe an unusual case of acute liver failure due to Hodgkin's lymphoma. CASE PRESENTATION AND INTERVENTION A 37-year-old man was admitted with jaundice and abdominal distension. Physical examination showed tender hepatosplenomegaly, ascites, grade I encephalopathy, left cervical (2 x 1 cm) and axillary (1 x 1 cm) lymph nodes. The laboratory data revealed elevated serum bilirub...

Acute hepatitis is seen sporadically round the year in Bangladesh. The incidence of acute viral hepatitis E increases after floods as this allows sewerage contamination of piped and groundwater. The aim of this retrospective study was to assess the burden of hepatitis E virus (HEV infection) in Bangladesh. Patients attending the Hepatology Unit III of the Bangabandhu Sheikh Mujib Medical Univer...