Active magnetic bearing (AMB) system has been recently employed widely as an ideal equipment for high-speed rotating machines. The inherent challenges to control the include instability, nonlinearity and constricted range of operation. Therefore, advanced technology is essential optimize AMB performance. This paper presents application model predictive (MPC) based on linear parameter-varying (L...

We determined the in vitro antifungal activity of liposomal amphotericin B (L-AmB) against 604 clinical yeast isolates. Amphotericin B deoxycholate (D-AmB) was tested in parallel against all the isolates. Susceptibility testing was performed according to the Clinical and Laboratory Standards Institute (CLSI) M27-A3 method. Overall, L-AmB was highly active against the isolates (mean MIC, 0.42 µg...

Conventional Active Magnetic Bearings (AMB) are operated using a bias current (or flux) to achieve greater linearity and dynamic capability. Bias, however, results in undesirable rotating losses and consequent rotor heating. While control without bias flux is an attractive alternative, it is considerably more complex due to both force slew rate limitations and actuator nonlinearity. In this pap...

objective: amphotericin b (amb) is an ancient antifungal drug and proper for treatment of systemic fungal infection. unfortunately, this antibiotic has shown some side effects such as nephrotoxicity. therefore, recently new amb formulated has been prepared for reduced toxicity and increased effectiveness. materials and methods: amb nanocapsules prepared from polymers such as poly d, l-lactide-...

Acknowledgments My special thank goes to my advisor Dr. Marcio S. de Queiroz. I thank him for all his continued support in all stages of this project. I would also like to extend my sincere gratitude to my committee members Dr. Kemin Zhou and Dr. Yitshak Ram for their valuable support and guidance. Abstract A solution to the problem of AMB control with reduced electrical power losses will be pr...

The aim of this work was to evaluate how an aqueous micellar system containing Amphotericin B (AmB) and sodium deoxycholate (DOC) can be rebuilt after heating treatment. Also, a review of the literature on the physicochemical and biological properties of this new system was conducted. Heated (AmB-DOC-H) and unheated (AmB-DOC) micelles were then diluted at four different concentrations (50 mg · ...

Sir—We read with interest the recent open-label study by Imhof et al. [1] reporting the tolerability of high-dose amphotericin B (AmB) deoxycholate (AmBd) administered by continuous infusion. Similar to previous reports [2, 3], continuously infused AMB-d was found to result in a lower rate of nephrotoxicity and fewer infusion-related reactions than did a 4-h infusion of AmB-d at the same daily ...

Theory and simulation results have demonstrated that four, variable speed flywheels could potentially provide the energy storage and attitude control functions of existing batteries and control moment gyros on a satellite. Past modeling and control algorithms were based on the assumption of rigidity in the flywheel’s bearings and the satellite structure. This paper provides simulation results a...

Amphotericin B (AmB) is excreted via the renal excretion route. This excretion process may result in nephrotoxicity. However, relevant information on the precise renal excretion mechanisms is not available. The aim of the study was to analyze the possible interaction of AmB or its prodrug AmB deoxycholate (AmB-DOC) with the typical renal organic anion transporters (OATs) and organic cation tran...