This review is focused on polyprenyl phosphatis (PPFs) (phosphorilated polyprenols), a unique class of natural compounds with wide spectrum biological activity. The main emphasis put their antiviral properties that were studied in numerous vitro and vivo experiments. results formed the basis for development new drugs containing PPFs as active substance. These drugs, due to high efficiency harml...

Nongenital herpes simplex virus type 1 is a common infection usually transmitted during childhood via nonsexual contact. Most of these infections involve the oral mucosa or lips (herpes labialis). The diagnosis of an infection with herpes simplex virus type 1 is usually made by the appearance of the lesions (grouped vesicles or ulcers on an erythematous base) and patient history. However, if un...

herpes simplex virus (hsv) is a worldwide contagious infection disease.  it usually transmitted during childhood via nonsexual contacts. one of the important causes of genital herpes in developed countries is hsvi. having knowledge about distribution and prevalence of this infection in pregnant women may help to choose an appropriate treatment and prevention methods. 65 pregnant women who have ...

Background and Aims: Herpes simplex virus (HSV) is responsible for several significant human viral diseases, with severity ranging from subclinical to fatal infection. Herpes simplex virus type 2 (HSV2) infections are more commonly seen in association with the genitalia and surrounding areas, and can be transmitted to newborns during childbirth. Generalized infections in newborns are also predo...

Herpes simplex virus infections of humans have been known since ancient times. Contemporary society has witnessed a series of devastating manifestations of herpes simplex virus infections--namely, genital herpes simplex virus infection and neonatal herpes simplex virus infection. With the evolution of society, particularly advances in birth control and increasing promiscuity, the seroprevalence...

statement of the problem: alveolar bone necrosis induced by herpes zoster infection is considered as a rare manifestation of osteomyelitis and few case reports are presented in the literature. purpose: the aim of this study was to evaluate mandibular osteomyelitis caused by herpes zoster in the immunocompromised patients with histopathologically documented osteomyelitis in the mandible and herp...

Herpes simplex is a common viral infection of the skin or mucous membranes. The lesions caused by this infection are often painful, burning, or pruritic, and tend to recur in most patients. Shortterm treatment with acyclovir can accelerate the healing of an acute outbreak, and continuous acyclovir therapy is often prescribed for people with frequent recurrences. While this drug can reduce the r...