Fibrinolytic enzymes have nowadays found important place in the medical field. Only few studies had reported the fibrinolytic enzyme production from actinomycetes. So the microbial fibrinolytic enzymes, especially those from actinomycetes, have the potential to be developed as drugs to prevent cardiovascular diseases. Actinomycetes were producing strong enzymes with no side effects, non pathoge...

UNLABELLED Soils host diverse microbial communities that include filamentous actinobacteria (actinomycetes). These bacteria have been a rich source of useful metabolites, including antimicrobials, antifungals, anticancer agents, siderophores, and immunosuppressants. While humans have long exploited these compounds for therapeutic purposes, the role these natural products may play in mediating i...

Actinomycetes are promising tool to control plant disease and to promote plant growth. In ayurved system of medicine rhizome portion of Curcuma longa L. was used as an antiseptic. Antimicrobial substances released from these plants diffuse into the surrounding soil area of the plant. Actinomycetes which grow in these areas are resistant to these substances. Different types of pesticide and chem...

Microbial pathogens are developing resistance against existing antibiotics, stressing the urgency for discovery of new therapeutic compounds. Actinomycetes, alone produce 70-80% of the available antibiotics. The chances of isolating undiscovered strains from the terrestrial habitats have diminished so that the search for novel products has switched to rare genera of actinomycetes from normal ha...

Colonization of host plants by microbial symbionts and avirulent parasites often elicits physiological modifications such as localized and systemic disease resistance1–4) and drought or dehydration tolerance5–7). Among such microbes, soil-inhabiting actinomycetes have attracted much attention as potential biocontrol agents in agriculture because of their ability to produce a variety of antibiot...

Interspecies interaction of actinomycetes will express new gene clusters and may therefore affect the pigmentation, sporulation and production of secondary metabolites. Actinomycetes strains were isolated from Howze Soltan Salt Lake. Binary actinomycete interaction assay was conducted to evaluate its effect on colony morphology and antibiotic production. The molecular identification of the indu...

Thermophilic actinomycetes, associated with a hypersensitivity pneumonitis, may be found in compost but also have been detected in heating systems of office buildings. This study was designed to determine whether these organisms were present in residential heating systems. Furnace dust or humidifier water of 12 of 20 homes contained thermophilic actinomycetes, indicating that the organisms may ...

Actinobacteria (actinomycetes) have been received much attention, as these bacteria pro‐ duce a variety of natural drugs and other bioactive metabolites. The distribution of acti‐ nomycetes in various natural habitats, including soil, ocean, extreme environments, plant, lichens and animals, is described. The collection and pretreatment of test samples from different sources, design principle of...

Genomic sequence data have revealed the presence of a large fraction of putatively silent biosynthetic gene clusters in the genomes of actinomycetes that encode for secondary metabolites, which are not detected under standard fermentation conditions. This review focuses on the effects of biological (co-cultivation), chemical, as well as molecular elicitation on secondary metabolism in actinomyc...

Actinomycetes are Gram-positive filamentous bacteria used as biocontrol agents against pathogens. Currently, little research on actinomycetes has been published in Indonesia. The study provides issues related to the most relevant keywords actinomycetes, productive authors and countries research, current future topics research. This paper aims understand status trend of biological control, espec...