By G. ADOLPH ACKERMAN A RARE and hitherto undescrihed vacuole-like structure has been found within the cytoplasm of certain leukemic cells from seven patiemits with acute leukemia. For descriptive purposes this cytoplasmic structure shall he designated as the granule-vacuole body. It was the purpose of this investigation to study the morphology and cytochemist.ry of this structure and (ompare i...

Dinsmore, Dempsey and Hazard, 1948 .. 8 Kellett and Sutherland, I949 .. .. 5 Dean, I949 .. .. .. .. .. 2 Roualle, 1950 .. .. .. 2 Dick and Kellett, I951 .. .. .. 2 Scott, 1952 .. .. .. .. .. 2 Brewer and Orr, 1953 .. .. .. 10 Walt, Woolner and Black, 1953 .. .. 21 Kenyon and Ackerman, I955 .. .. 2 Lindsay and Dailey, I955 .. .. 8 Canney, I956 .. .. .. .. Canklin and Gent, 1957 .. .. .. Cureton,...

Formin Homology 2 Domain Containing 3 Variants Associated With Hypertrophic Cardiomyopathy Eric C. Wooten, PhD; Virginia B. Hebl, MD; Matthew J. Wolf, MD, PhD; Sarah R. Greytak, PhD; Nicole M. Orr, MD; Isabelle Draper, PhD; Jenna E. Calvino, BA; Navin K. Kapur, MD; Martin S. Maron, MD; Iftikhar J. Kullo, MD; Steve R. Ommen, MD; J. Martijn Bos, MD, PhD; Michael J. Ackerman, MD, PhD; Gordon S. Hu...

N. gonorrhoeae is a species which was originally highly sensitive to penicillin (Cohn and Seijo, 1944; Frisch, 1944; Carpenter, Bahn, Ackerman, and Stokinger, 1945; Lankford, 1945; Meads, Ory, Wilcox, and Finland, 1945; Romansky, 1946; Kenedy and Alfoldy, 1947; Romansky and Robin, 1947; Hughes and Carpenter, 1948; Hawks and Greey, 1948; Cohn, Grunstein, Goldberg, and Crane, 1949; Mills, 1949; S...

Data flow deeds with nets of concurrently communicating agents. But unlike other theories of concurrency, the main concern here is about the I(nput)-O(u-tput) behavior of a system. The Kahn principle states that for special dctermlnistic agents the Input-Output behavior of a net can bc obtained from the I-O behaviors of its components. The I-O behaviors of Kahn agents are sequential functions a...

D r Ackerman proposes that dermatologists should send all their slides to a dermatopathologist. In my opinion, this is really a scope of practice argument where one subspecialty is arguing that only they should get all the referrals. Dr Ackerman has suggested that his opinion is an ethical point. I would disagree. His point of view that dermatologists are greedy because they do not send all the...

In recent years many publications have appeared on the use of tetracycline fluorescence for detecting malignancy, especially of the stomach (Klinger and Katz, 1961 ; Sandlow, Allen, and Necheles, 1963 ;Berk and Kantor, 1962; Berk and Kantor, 1963; Sherman, Chryssanthou, Sukoff, Mininberg, Beckman, and Weingarten, 1963; Vassar, Saunders, and Culling, 1960; Ackerman and McFee, 1963; Berk, 1963; S...

OBJECTIVE A computational model of insulin secretion and glucose metabolism for assisting the diagnosis of diabetes mellitus in clinical research is introduced. The proposed method for the estimation of parameters for a system of ordinary differential equations (ODEs) that represent the time course of plasma glucose and insulin concentrations during glucose tolerance test (GTT) in physiological...

Traditional mean-field rate equations of chemical kinetics for spatially uniform systems1−3 and the corresponding reaction−diffusion equations describing spatial heterogeneity4−6 have proved immensely useful in elucidating catalytic processes. However, it is well-recognized that standard mean-field rate expressions neglect spatial correlations in the reactant and/or product distribution. It is ...