نتایج جستجو برای: acetyl cholinesterase
تعداد نتایج: 30586 فیلتر نتایج به سال:
Wild artichoke (Cynara cornigera), a thistle-like perennial belonging to the Asteraceae family, is native to the Mediterranean region, northwestern Africa, and the Canary Islands. While the pleasant, albeit bitter, taste of the leaves and flowers is attributed to the sesquiterpene lactones cynaropicrin and cynarin, a comprehensive phytochemical investigation still needs to be reported. In this ...
Alzheimer's disease (AD) is the most common form of dementia among older people and the pathogenesis of this disease is associated with oxidative stress. Acetylcholinesterase inhibitors with antioxidant activities are considered potential treatments for AD. Some novel ketone derivatives of gallic hydrazide-derived Schiff bases were synthesized and examined for their antioxidant activities and i...
Background and Purpose: The wide spread usage of pesticides for improving agricultural programs is a risk factor of acute and chronic human poisoning, especially farmers. Diazinon is one of the most common organophosphates insecticides that cause oxidative stress and lipid peroxidation. The mechanism of organophosphates is postulated to be non-irreversible anticholinesterase action. This study ...
The present study evaluates the insecticidal activity of two essential Oil (EOs) mint (Mentha arvensis), and ajwain (Carum capyicum) against pulse beetle (Callosobruchus chinensis) (L). Contact toxicities these were evaluated using parameters lifecycle like total development period, numbers eggs laid, adult emergence longevity. Along with detoxification enzyme inhibition activities acetyl choli...
Culex pipiens (L.) (Diptera: Culicidae) is the most important medical insect in many parts of world. Biological and natural chemicals have advantages over traditional ones case mosquito control. The efficacy two insecticides belonging to different groups chlorpyrifos-ethyle (oranophosphate) Bacillus thuranginsis var israelinsis) (bio-insecticides)were evaluated against field laboratory individu...
Slices of rat caudate nuclei were incubated in vitro in media containing, among other constituents, three different concentrations of glucose (0.5, 2 and 10 mM), 0.2 mM-choline, paraoxon as an inhibitor of cholinesterase, and 5 mM- or 30 mM-K+. After 30 and 60 min of incubation, the concentrations of acetyl-CoA, acetylcholine and choline in the tissue and of acetylcholine in the incubation medi...
This study was designed to evaluate the protective effect of N-acetyl cysteine in reducing methylmercury (MeHg)-induced oxidative stress, lipid peroxidation, DNA damage in liver, kidney, and brain, and their ability to restore altered hepatic, renal, and other biochemical variables. Male Sprague-Dawley rats (150±10 g) were randomly divided into three groups. Group 1 served as the control. Group...
Carbamate insecticides act similarly to the organophosphates in that they inhibit acetyl cholinesterase enzyme (AChE) at nerve synapses and neuromuscular junctions. This inhibition is reversible with spontaneous hydrolysis occurring usually within several hours [1] thus, the inhibition of blood AChE is frequently not evident at the laboratory [2]. There are two main pharmacokinetic characterist...
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