The Bacillus subtilis endospore coat protein CotA shows laccase activity. By using comparative modeling techniques, we were able to derive a model for CotA based on the known x-ray structures of zucchini ascorbate oxidase and Cuprinus cereneus laccase. This model of CotA contains all the structural features of a laccase, including the reactive surface-exposed copper center (T1) and two buried c...

Protein hydrolysate is highly regarded as a source of naturally occurring antioxidant peptides. The purpose of this study was to investigate the effect of Ultrasonic (Frequency, 20 KHz; Amplitude, 50%; Time, 30 min) and high-pressure homogenization (Power, 1500 bar; Rated flow, 10 dm/h) pretreatmenton the enzymatic hydrolysis and antioxidant properties of yeast protein hydrolysate obtained from...

The health benefits of green and black tea are mainly associated with their antioxidant potential and phenolic compounds. The present study aimed to evaluate the effects of dried rose petals (Rosa damascena) on the antioxidant capacity of green and black tea. Antioxidant capacities of tea and rose infusions were assessed using 2, 2-diphenyl-1-picrylhydrazyl (DPPH) and 2, 2-azinobis-3-<...

BACKGROUND Nonea micrantha Boiss. & Reut . being an unexplored member of Boraginaceae was investigated for GC/MS analysis, acetylcholinesterase (AChE), butyrylcholinesterase (BChE) inhibitory and antioxidant activities in an attempt to find its effectiveness in neurological disorders. METHODS The AChE and BChE inhibitory activities of crude methanolic extract (Nm.Cr), subsequent fractions; n-...

BACKGROUND Co-products obtained from pomegranate juice processing contain high levels of polyphenols with potential high added values. From value-addition viewpoint, the aim of this study was to evaluate the stability of polyphenolic concentrations in pomegranate fruit co-products in different solvent extracts and assess the effect on the total antioxidant capacity using the FRAP, DPPH˙ and ABT...

BACKGROUND Laccases are multi-copper oxidases that catalyze the one electron oxidation of a broad range of compounds. Laccase substrates include substituted phenols, arylamines and aromatic thiols. Such compounds are activated by the enzyme to the corresponding radicals. Owing to their broad substrate range laccases are considered to be versatile biocatalysts which are capable of oxidizing natu...

Differences in the antioxidant system, apoptotic mechanism and in cell cycle between prostatic cell lines could partially elucidate the development of cisplatin resistance. The aim of this study was to identify the most characteristic parameter for a particular cell line and/or a particular cisplatin treatment using a general regression model and to assess whether it is possible to use measured...

objective: the aim of this study was to determine the oxidative stress; serum level of total antioxidant capacity (tac)and malondialdehyde (mda) level and the depression score among the depressed rotational shift workers in shahid tondgouyan refinery in tehran (iran). methods: a cross-sectional study was conducted among all the 189 shift workers in shahid tondgouyan oil refinery who were eligib...