A 41-year-old man was referred with a complaint of visual loss in his left eye and his best corrected visual acuity was 20/80. Slit lamp examination showed arborizing conjunctival vessels and dry eye. Fundus examination and fluorescein angiography revealed a non-ischemic central retinal vein occlusion. Cardiovascular, rheumatologic, and hematologic work up showed no abnormal findings. An ascert...

Sox2 is a transcriptional regulator that is highly expressed in retinal astrocytes, yet its function in these cells has not previously been examined. To understand its role, we conditionally deleted Sox2 from the population of astrocytes and examined the consequences on retinal development. We found that Sox2 deletion does not alter the migration of astrocytes, but it impairs their maturation, ...

With the advancement of CAD (Computer Assisted Diagnosis) Image Processing in Medical Field has created its own niche. Retinal Blood Vessels are highly complicated with low contrast and of very thin diameter which often causes failure in diagnosis of exact abnormalities. However, many researchers have worked on enhancement and segmentation of Retinal Blood Vessels through various methods over t...

IMPORTANCE Paravascular retinal abnormalities are common in highly myopic eyes. However, affected areas may be underestimated, and the pathogenesis and effects on retinal function remain unclear. OBJECTIVE To prospectively investigate the characteristics and pathogenesis of paravascular inner retinal defects (PIRDs). DESIGN, SETTING, AND PARTICIPANTS Prospective and observational case serie...

In sickle cell retinopathy vascular involvement is most frequently recognised at the retinal periphery, but obstruction of perimacular arterioles and of major retinal vessels may also occur. This report describes a patient with homozygous sickle cell (SS) disease with recurrent occlusion of major retinal vessels associated with recurring transient impairment of visual function.

Purpose The purpose of this study was to characterize a novel finding that relative positions of choroidal and retinal vessels change over time in preterm infants and to identify factors associated with this finding using quantitative analysis. Methods Fundus images were obtained prospectively through a retinopathy of prematurity (ROP) cohort study. Images were excluded if choroidal vessels c...

The thesis aims to investigate the performance and potential of wavelets in the context of feature detection in retinal imaging, and to use those results to develop a robust algorithm that can reliably detect the blood vessels within retinal photographs. Detection of blood vessels in retinal images is an important step in the predictions and diagnosis of cardio-vascular diseases, such as hypert...

Diabetic retinopathy is a complication of type 2 diabetes resulting from long-term accumulated damage to retinal blood vessels and one the life-threatening complications most common cause acquired blindness in adults it affects 93 million people worldwide.

PURPOSE To assess the effects of retro-orbital (RO) injection of fluorescein isothiocyanate dextran (FITC-dextran) for observing mouse retinal vessels. METHODS Oxygen-induced retinopathy (OIR) was induced in 7-day postnatal (P7) C57BL/6J mice by exposing them to a 75% oxygen atmosphere for 5 days and then returning them to room air at P12. At P17, 45 P17 OIR mice and 12 normal mice received a...