نتایج جستجو برای: abcd2
تعداد نتایج: 187 فیلتر نتایج به سال:
Jennifer E. Fugate, DO Alejandro A. Rabinstein, MD In this journal club article, we evaluate a study by Giles and colleagues1 that reports stroke risk in patients with classically defined TIA subcategorized by presence or absence of radiologic brain infarction. The concept of a TIA is evolving in parallel with better understanding of brain ischemia and insights gained from neuroimaging studies....
Peroxisomes catalyze a range of essential metabolic functions, mainly related to lipid metabolism. However, their roles in obesity have yet to be clarified. The aim of this study was to investigate the correlation between obesity and peroxisomal lipid metabolism, particularly very long-chain fatty acid (VLCFA) metabolism, gene expression of peroxisomal β-oxidation enzymes, peroxisomal ATP-bindi...
BACKGROUND AND PURPOSE Several risk scores have been developed to predict the stroke risk after transient ischemic attack (TIA). However, the validation of these scores in different cohorts is still limited. The objective of this study was to elucidate whether these scores were able to predict short-term and long-term risks of stroke in patients with TIA. METHODS From the Fukuoka Stroke Regis...
OBJECTIVE Urgent evaluation and treatment of transient ischemic attack (TIA) patients in a dedicated TIA clinic may reduce the 90-day stroke risk by 80%. ABCD2 (Age, Blood pressure, Clinical features, Duration, Diabetes) score and magnetic resonance imaging abnormalities help to identify patients at high risk of stroke. Our aim was to determine whether the use of transcranial Doppler (TCD) exam...
X-linked adrenoleukodystrophy (X-ALD; OMIM 300100), the most frequent peroxisomal disorder, presents as a severe neurodegenerative disease with widely varying clinical phenotypes. The biochemical characteristic of X-ALD is the accumulation of very long-chain fatty acids (VLCFA), which should normally be degraded by the peroxisomal b-oxidation pathway, in plasma and tissues of X-ALD patients. It...
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