Miconia is one of the largest genus of the Melastomataceae, with approximately 1,000 species. Studies aiming to describe the diverse biological activities of the Miconia species have shown promising results, such as analgesic, antimicrobial and trypanocidal properties. M. albicans leaves were dried, powdered and extracted to afford chloroformic and methanolic extracts. Total phenolic contents i...

Various methods employed in evaluating antioxidant activities of various samples gives varying results depending on the specificity of the free radical or oxidant used as a reactant. This study investigated the antioxidant /radical scavenging properties of the methanolic extract of Vernonia amygdalina (MEVA) leaves and studied the relationship between the assay methods. Antioxidant capacity of ...

Exposure to radiation or 2.2′Azobis(2-amidopropane) dihydrochloride (AAPH) induces generation of reactive oxygen species (ROS) especially hydroxyl radical (OH) and peroxyl radical (ROO), which are capable of inducing lipid peroxidation. Our earlier studies have demonstrated that extracts of the medicinal and edible mushrooms Ganoderma lucidum, Pleurotus florida, Pleurotus sajor-caju and Phellin...

Chemical investigation of aerial parts of Schkuhria pinnata var wislizeni (Asteraceae) allowed the characterization of the sesquiterpene lactones 1, 2 and 5, the flavonoids 3 and 4, and the acyl phenyl propanoids 10 and 11. Structure 2, named dischkuhriolin, was confirmed as a Diels Alder adduct of 1 as dienophile and a guaianolide as diene. Spectroscopic analysis of 5 and its diacetyl derivati...

ilex spinigera (aquifoliaceae) plant is an evergreen tree or shrub with thick glossy dark green leaves and red fruits. this plant has medicinal properties and has been used traditionally in northern iran for malaria treatment. the aim of this work is to evaluate the antioxidative activities and the inhibitory effect of i.spinigera on the oxidation of dna. we have found no reports about the popu...

The antioxidant activities of natural d-alpha-tocopherol, mixed tocopherols and tocotrienols, and formulations comprising all forms of vitamin E, providing 400 IU, were determined employing an improved oxygen radical absorbance capacity (ORAC) assay using fluorescein (FL) as the fluorescent probe, randomly methylated beta-cyclodextrin (RMCD), 2,2'-azobis(2-amidino-propane)dihydrochloride (AAPH)...

Introduction. Determination of antioxidant activity using a biological method is important in predicting antioxidant capacity in vivo. The Caco-2 cell-based antioxidant activity (CAA) assay quantifies antioxidant activity in Caco-2 cells and has proved to possess good biological relevance. The aim of this study was to determine the CAA of 25 fruits commonly consumed in China, along with total p...

The aim of this study was to synthesize and examine possible in vitro antioxidant effects of indole-based melatonin analogue compounds. As a part of our ongoing study nineteen indole hydrazide/hydrazone derivatives were synthesized, characterized and their in vitro antioxidant activity was investigated by three different assays: by evaluating their reducing effect against oxidation of a redox s...