OBJECTIVE To estimate the intraocular pressure (IOP)-lowering effect of prostaglandin analogs (PGAs) when added to topical β-blocker (BB) therapy. DESIGN Systematic review and meta-analyses of randomized clinical trials. PARTICIPANTS Twenty-nine articles reporting on 33 study arms and 3 control arms. METHODS Articles published between January 1, 1990, and August 18, 2009, were identified ...

BACKGROUND AND PURPOSE A new Glasgow Coma Scale-based scale has been developed to predict patient outcome in subarachnoid hemorrhage by calculating cut-off points by which 2 consecutive categories corresponded to a statistically significant different outcome. We assessed the external validity of this Prognosis on Admission of Aneurysmal Subarachnoid Hemorrhage (PAASH) scale and compared it to t...

PURPOSE Airway pathology in children with atopic asthma can be reflected by the concave shape of the maximal expiratory flow-volume (MEFV) curve and high fractional exhaled nitric oxide (FeNO) values. We evaluated the capacity of the curvilinearity of the MEFV curve, FeNO, and their combination to distinguish subjects with atopic asthma from healthy individuals. METHODS FeNO and angle β, whic...

introduction: several mechanisms were introduced as causes of serum creatinine phosphokinase (cpk) raise in intoxicated patients. this study aimed to assess the relationship between serum cpk level in the first 24 hours and baseline characteristics as well as outcomes of these patients. methods: this one year retrospective cross-sectional study was conducted on all intoxicated patients, who wer...

BACKGROUND Bedside inferior vena cava (IVC) ultrasound has been proposed as a non-invasive measure of volume status. We compared ultrasound measurements of the caval index (CI) and physician gestalt to predict blood pressure response in patients requiring intravenous fluid resuscitation. METHODS This was a prospective study of adult emergency department patients requiring fluid resuscitation....

Background: Edinburgh Postnatal Depression Scale (EPDS) has been used as a reliable screening tool for postpartum depression in many countries. This study aimed to assess the psychometric properties and diagnostic accuracy of the EPDS in a sample of Iranian women. Methods: Using stratified sampling 262 postpartum women (2 weeks-3 months after delivery) were selected from urban and rural health ...

Background: Early diagnosis of gestational diabetes is one of the most important applications of taking care of during pregnancy. The current study was done to find the correlation between hemotocrit in the first trimester of pregnancy with gestational diabetes in women who referred to Milad Hospital in Tehran in 2009-2010. Materials and Methods: A prospective cohort study was conducted on 700 ...