Transformation of murine adult bone marrow cells by Abelson Murine Leukemia Virus (A-MuLV)' can result in the generation of permanent cell lines (Abelson lines) representing early stages of B lymphocyte differentiation (1) . Because it is difficult to obtain large numbers of B cell precursors capable of Ig gene recombination from normal cell populations, Abelson cell lines provide an accessible...

Although the cellular origin of Reed-Sternberg (RS) cells of classical Hodgkin's disease (HD) has been a controversial issue for many years, recent immunophenotypic and molecular studies have suggested that RS cells of a subset of classical HD cases may be related to B cells. To further define the immunophenotypic features and the differentiation stage of RS cells, a series of 56 HD samples, in...

The attachment glycoprotein G plays a major role in the antigenic variability of respiratory syncytial (RS) virus. We have expressed from recombinant baculoviruses antigenic group A and group B RS virus G proteins (designated bacAG for the group A and bacBG for the group B virus G protein). The insect cell-produced G proteins migrated more rapidly in SDS-PAGE as compared to HEp-2 cell derived G...

Radiation leukaemia virus, Rs strain (RadLV-Rs), is a virus complex derived from radiation-induced lymphoma of the C57BL/6 mouse. Several B-ecotropic retroviruses (T1223/B, T98/B and T128/B) were isolated from the RadLV-Rs and further cloned. They were found to be highly leukaemogenic and polymorphic in terms of XC cell fusion activity. To investigate a possible relationship between their pheno...

BACKGROUND The aim of the study was to evaluate serum parameters of lipid metabolism, homocysteine, soluble adhesion molecules and common carotid artery wall thickness in children from families with early symptoms of atherosclerosis. METHODS The first stage included 137 pairs of mothers and newborns, and the second 18 children from the same group (age 18-30 months) and their parents (age 21-4...

Richter syndrome (RS) derives from the rare transformation of chronic lymphocytic leukemia (CLL) into an aggressive lymphoma, most commonly of the diffuse large B cell lymphoma (DLBCL) type. The molecular pathogenesis of RS is only partially understood. By combining whole-exome sequencing and copy-number analysis of 9 CLL-RS pairs and of an extended panel of 43 RS cases, we show that this aggre...

Wronkowska M., Soral-Śmietana M. (2012): Fermentation of native wheat, potato, and pea starches, and their preparations by Bifidobacterium – changes in resistant starch content. Czech J. Food Sci., 30: 9–14. The capability was studied of the selected Bifidobacterium strains to utilise the resistant starch fraction (RS) from native starches of the following origin: wheat, potato, and pea, and th...

Three novel 36-membered macrolide antibiotics, RS-22A, B and C produced by Streptomyces violaceusniger have been isolated. These antibiotics were purified from an acetone extract of the mycelia followed by butanol extraction, centrifugal partition chromatography and HPLC. RS-22A, B, C showed antimicrobial activity against fungi and Gram-positive bacteria.