With dual-radiopharmaceutical (DR) parathyroid scintigraphy, imaging with 99mTcO4-or 123I-NaI is combined with 99mTc-sestamibi scintigraphy for localization of parathyroid adenomas. The set images are then either visually compared or digitally subtracted to aid in interpretation. While both EANM and SNMMI guidelines recommend use of digital subtraction over visual interpretation alone, to date,...

In patients with coronary artery disease, the distinction between scar and viable myocardium by means of myocardial perfusion imaging (MPI) sometimes can be difficult because of the equivocal meaning of fixed perfusion defects. In this study we examined whether addition of a 99mTc-sestamibi infusion study to the standard MPI could provide extra information regarding the fixed defects. Thirty-se...

BACKGROUND 99mTc-sestamibi parathyroid SPECT scintigraphy is a useful tool in the pre-operative study of hyperparathyroidism. False negatives (FN) have been reported in 5.7-14% of the examinations. AIM To characterize 99mTc-sestamibi FN in cases referred for primary hyperparathyroidism (PHP) to a university hospital. MATERIAL AND METHODS Descriptive retrospective analysis. We included patie...

Myocardial perfusion scintigraphy with technetium99m-Sestamibi (99mTc-sestamibi) allows early detection and evaluation of disease extension and cardiovascular risk in patients with suspected or established CAD, helping in decision-making regarding the start and type of therapy to be implemented.1 This method has been widely used, but shows difficulties in some situations such as balanced multiv...

BACKGROUND Exercise gated single-photon emission computed tomography (SPECT) using technetium-99m (99mTc)-sestamibi evaluates both myocardial perfusion during stress and wall motion >30 min after the stress, which has the potential to assess not only exercise-induced myocardial ischemia but also the development of myocardial stunning. METHODS AND RESULTS To evaluate the incidence of post-stre...

INTRODUCTION Dobutamine stress echocardiography (DSE) and myocardial perfusion scan (MPS) are commonly used to detect viable myocardium. We designed this study to compare the results of these two methods in detecting myocardial viability. METHODS We studied 736 segments from 46 patients (42 men, mean age 56 years), with coronary artery disease and impaired left ventricular systolic function (...

introduction:patients with the coronary slow flow phenomenon (scf) frequently experience angina episodes. the purpose of this study was to determine efficacy of nicorandil in myocardial perfusion in patients with scf. methods: twenty patients (50.85 ± 12.96 y) with scf were studied.  we evaluate coronary slow flow according to protracted thrombolysis in myocardial infarction (timi) frame count....