نتایج جستجو برای: 99mtc labelled

تعداد نتایج: 25248  

Journal: :Gut 1995
N Davies H Kynaston J Yates B A Taylor S A Jenkins

The inhibitory effect of octreotide on the growth of liver tumour is probably mediated (at least in part) by stimulation of the hepatic reticuloendothelial system (RES) activity. This study therefore investigated the effect of octreotide on the hepatic and splenic RES (assessed by the uptake of technetium 99m labelled albumin colloid, 99mTc-AC) in normal and tumour bearing rats and in animals t...

Journal: : 2022

Objective: The development of new radiopharmaceuticals capable specifically imaging cancer is an important research area. For this reason, the aim study to investigate cell binding novel developed nanoradiopharmaceutical ([99mTc]Tc-nab-PTX) on HT-29 line (human colorectal adenocarcinoma cells).
 Material and Method: In study, nab-PTX was labeled with [99mTc]Tc, labeling efficiency in vitro...

Journal: :Journal of clinical pathology 1976
C S Bowring H I Glass S M Lewis

The rate of uptake in the spleen of heat-damaged red blood cells labelled with 99mTc has been measured by radioisotope scanning in 38 patients. The values obtained for the half-clearance time into the spleen using this method have been compared with the values obtained simultaneously by blood sampling for the rate of loss of radioactivity from the circulation. It was found that the uptake into ...

Journal: :Nuclear medicine review. Central & Eastern Europe 2006
Daniela Chroustová Vladimír Volf Valér Dzupa Pavel Kryl Václav Mandys

The case of an 11-year-old boy with recurrent abdominal pain is presented. Physiological findings were found normal during a clinical investigation, as well as many laboratory tests, ultrasonography and CT of abdomen. Only a high level of sedimentation rate and the focus of increased activity in the sacral region on scintigraphy using 99mTc-HMPAO (hexamethypropyleneaminooxime) labelled leukocyt...

2018
Yvonne W. S. Jauw Marc C. Huisman Tapan K. Nayak Danielle J. Vugts Randolph Christen Valerie Meresse Naegelen Dominik Ruettinger Florian Heil Adriaan A. Lammertsma Henk M. W. Verheul Otto S. Hoekstra Guus A. M. S. van Dongen C. Willemien Menke-van der Houven van Oordt

BACKGROUND Ideally, monoclonal antibodies provide selective treatment by targeting the tumour, without affecting normal tissues. Therefore, antibody imaging is of interest, preferably in early stages of drug development. However, the imaging signal consists of specific, as well as non-specific, uptake. The aim of this study was to assess specific, target-mediated uptake in normal tissues, with ...

Journal: :The Journal of bone and joint surgery. British volume 1986
E P Szypryt J G Hardy C L Colton

Radiopharmaceuticals have been successfully used to detect occult neoplasms and infective lesions. Bone scans using 99mTc-labelled methylene diphosphonate located osteoid osteomas accurately in a series of 30 symptomatic patients. A portable radiation detector system has been designed to help intra-operative localisation and facilitate complete excision of the lesions with minimal damage to nor...

Journal: :Thorax 1993
L E Nery R T Florencio P R Sandoval R T Rodrigues G Alonso G R Mason

BACKGROUND Increased pulmonary epithelial permeability evaluated by the rate of clearance from lung to blood of the radioaerosol solute technetium-99m labelled diethylenetriamine pentaacetate (99mTc-DTPA) has been reported in smokers and in workers exposed to silica dust. A study was carried out to determine whether there are additive effects of cigarette smoke and exposure to silica dust on cl...

Journal: :Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 1998
E Ripoll-Hamer E F De-Paula L C Freitas M J Pereira L M Fonseca B Gutfilen J J Carvalho L C Pôrto M Bernardo-Filho

In the present study we evaluated the binding of the radiopharmaceuticals sodium pertechnetate (Na 99mTcO4), methylenediphosphonic acid (99mTc-MDP) and glucoheptonate acid (99mTc-GHA) to blood elements using centrifugation and radioautographic techniques. Heparinized blood was incubated with the labelled compounds for 0, 1, 2, 3, 4, 6 and 24 h. Plasma (P) and blood cells (BC) were isolated and ...

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