The objective of this study was to investigate clinical utility of a graphical method for estimating liver uptake and blood retention of 99mTc-DTPA-galactosyl human serum albumin (99mTc-GSA; DTPA is diethylenetriaminepentaacetic acid) using dynamic single photon emission computed tomography (SPECT) data. When considering the kinetics of 99mTc-GSA, if it is assumed that (1) 99mTc-GSA distributes...

We present a patient with Fanconi syndrome who demonstrated poor renal uptake of 99mTc-DMSA and high urinary concentration of the tracer. A 99mTc-DTPA scan was normal and the creatinine clearance only minimally decreased. These findings suggest that 99mTc-DMSA may be accumulated in the kidney by glomerular filtration and subsequent tubular reabsorption, with the nonabsorbed fraction appearing i...

introduction: renal dynamic study is a well-established and popular test in routine practice of nuclear medicine. the test is non-invasive, rapid and unique in evaluation of the kidney function. in despite of its clinical values, the parameters derived from renogram are physiologically meaningless. that is due to the fact that renogram is not the true kidney function. from mathematical points o...

Introduction: Clinical radiation nephropathy can result in considerable morbidity and/or mortality. Renal tolerance (TD5/5) has been stated to be 20 Gy when irradiation has been delivered to both kidneys in 3-5 weeks. Therefore to minimize renal toxicity in these patients, localization and shielding of the kidneys are essential. This study was carried out to evaluate the role of 99mTc-DTP...

SCINTIGRAPHIC VISUALIZATION OF ABDOMINAL LYMPH NODES WITH 99mTc-PERTECHNETATE-LABELED SULFUR COLLOID Virgil F. Fairbanks, W. Newlon Tauxe, Joseph M. Kiely, and W. Eugene Miller 185 EFFECT OF LINE SPACING AND RATEMETER AVERAGING ON LESION DETECTION L. G. Knowles, E. F. Hart, and A. G. Schulz 191 CLINICAL EVALUATION OF °TGa-CITRATE SCANNING T. Higasi, Y. Nakayama, A. Murata, K. Nakamura, M. Sugi...

Captopril facilitates detection of unilateral renovascular hypertension by selectively reducing glomerular filtration rate in affected kidneys. To determine if volume depletion augments this response, we compared the effects of captopril, furosemide, and combined furosemide plus captopril on individual kidney computer-derived clearances of 99mTc-diethylenetriamine pentaacetic acid (DTPA) and [1...