DHT based Peer-to-Peer (P2P) algorithms are very promising for their efficient routing performance. However, most commercial P2P systems donot adapt DHT algorithms and still use central facilities or broadcasting based routing mechanisms. One reason impeding the DHT algorithm popularity is the routing information maintenance overhead in DHT algorithms, it generates considerable network traffic ...

BACKGROUND Gonadal steroids, in particular 5 alpha-dihydrotestosterone (DHT) and 17 beta-estradiol (E2), have been shown to feed back on the hypothalamic-pituitary-gonadal (HPG) axis of the ranid frog. However, questions still remain on how DHT and E2 impact two of the less-studied components of the ranid HPG axis, the hypothalamus and the gonad, and if the feedback effects are consistently neg...

Dihydrotestosterone (DHT) binding to androgen receptors (AR) in hair follicles is commonly accepted as the first step leading to the miniaturizing of follicles associated with androgenetic alopecia (AGA). Testosterone is converted to DHT by the enzyme 5alpha-reductase. Finasateride a 5alpha-reducase inhibitor blocks the production of DHT and is currently used to treat AGA. The inhibition is not...

In this paper, we present an overview of factors affecting the performance of the DHT-algorithms and give examples of how these factors have been measured from the DHT algorithms. We analyse the strengths and weaknesses of evaluation methods that are based on simulation, and make observations on the growing importance of globally distributed testbeds such as PlanetLab. We conclude that the best...

Adiponectin, together with adipocyte size, is the strongest factor associated with insulin resistance in women with polycystic ovary syndrome (PCOS). This study investigates the causal relationship between adiponectin levels and metabolic and reproductive functions in PCOS. Prepubertal mice overexpressing adiponectin from adipose tissue (APNtg), adiponectin knockouts (APNko), and their wild-typ...

PURPOSE Neuropeptide growth factors such as bombesinare implicated in progression to androgen-independent prostate cancer (PC). We examined the impact of bombesin on androgen receptor (AR)-mediated gene expression. EXPERIMENTAL DESIGN The AR together with the AR-responsive probasin ARR(3)tk-luc or PSA-pPUE-ELB-luc promoter was cotransfected into Swiss 3T3 and PC-3 cells, both of which express...

Dihydrotestosterone (DHT) exerts both functional and signaling effects extending beyond the effects of testosterone in rodent skeletal muscle. As a primer for investigating the role of DHT in human skeletal muscle function, this study aimed to determine whether circulating DHT is acutely elevated in men following a bout of repeat sprint exercise and to establish the importance of training statu...

Intratumoural dihydrotestosterone (DHT) synthesis could be an explanation for castration resistance in prostate cancer (PC). By using liquid chromatography-mass spectrometry, we evaluated the intratumoral DHT synthesis from 5α-androstane-3β,17β-diol (3β-diol), which is inactive androgen metabolized from DHT. 3β-diol had biochemical potential to be converted to DHT via three metabolic pathways a...

Studying deployed Distributed Hash Tables (DHTs) entails monitoring DHT traffic. Commonly, DHT traffic is measured by instrumenting ordinary peers to passively record traffic. In this approach, using a small number of peers leads to a limited (and potentially biased) view of traffic. Alternatively, inserting a large number of peers may disrupt the natural traffic patterns of the DHT and lead to...

Although a distributed index on a distributed hash table (DHT) enables efficient document query processing in Peer-to-Peer information retrieval (P2P IR), the index costs a lot to construct and it tends to be an unfair management because of the unbalanced term frequency distribution. We devised a new distributed index, named Huffman-DHT, for P2P IR. The new index uses an algorithm similar to Hu...