The aim of the present study was to determine the mechanisms underlying the relaxant effect of adrenomedullin (AM) in rat cavernosal smooth muscle (CSM) and the expression of AM system components in this tissue. Functional assays using standard muscle bath procedures were performed in CSM isolated from male Wistar rats. Protein and mRNA levels of pre-pro-AM, calcitonin receptor-like receptor (C...

Methods Thirty children (aged 6 months to 11 years) with suspected CMPA were enrolled. They underwent skin prick tests and bouble-blind, placebo controlled food challenge to CMP. After confirming the diagnosis of CMPA, patients received fresh AM in a open challenge. Specific serum CMP and AM IgE, and biochemical parameters in blood were also assessed. Auxological evaluations were performed in a...

BACKGROUND The success of haematopoietic (bone marrow or peripheral blood) stem cell transplantation (SCT) is compromised by pulmonary complications. We hypothesised that a proinflammatory alveolar microenvironment, reflected in alveolar macrophage (AM) cytokine production, would predispose to such complications. METHODS AM were isolated from adult SCT recipients by bronchoalveolar lavage bef...

AM-6 with high intensity visible light absorption at 400-800 nm was synthesized via a hydrothermal route in the presence of F(-) ions. Structure characterization and DFT calculations indicate that the unusual optical properties originate from the connection of octahedral VO(6) wires with distorted tetrahedral VO(4) units, which are stabilized in the framework of AM-6.

Background:  Hydrogen has been demonstrated can selectively reduce the hydroxyl, which is the main cause of ionizing radiation-induced damage. Amifostine (AM) is the only radioprotective drug approved by the U.S. Food and Drug Administration for use in radiotherapy. The purpose of the present study was to investigate the combined radio-protective effect of hydrogen rich water (HRW) and AM....

Abstract A field experiment was conducted to investigate the influence of agricultural machines (AM) LDSM and Nordsten planting depths (PD) on wheat/ Abu-Ghraib 3 cultivar. The included two types AM (LDSM Nordsten) three PD levels (PD1 6, PD2 8 PD3 11 cm) application. split -split plot arrangement in RCBD with replications used, results indicated that (Nordsten type) major impact than all studi...

pathogenic infection in tasar silkworm, antheraea mylitta drury. is common and there is a breed specific response regarding tolerance. observations reveal the possibility of differential response by haemocytes to microbial infection in different breeds. hence, the susceptibility of three eco-races of tasar silkworm viz. daba, sarihan and raily to antheraea mylitta cytoplasmic polyhedrosis virus...

3-Acyl-5-( 1 -am inoalkylidene)-4-hydroxy-2 Hpyran-2,6(3 //)-d ione derivatives carrying lipophilic am ino groups were found to be highly potent inhibitors o f photosynthetic electron transport, and bo th the acyl and the am inoalkylidene groups on the pyran ring appeared to be indispensable for high activity. The structural features needed for activity in the 3-acyl-5(l-am inoalkylidene)-4-hyd...

abstract  introduction: smoking is an important risk factor of coronary artery disease. nicotine replacement therapy (nrt) for smoking cessation should be considered, especially in coronary patients. methods: twenty-four healthy smokers, smoking an average of 20 cigarettes a day for 15 years and with moderate cigarette dependence (according to the fagershtrum questionnaire score) were randomly ...