BACKGROUND In response to the increase in obesity, pharmacologic treatments for weight loss have become more numerous and more commonly used. PURPOSE To assess the efficacy and safety of weight loss medications approved by the U.S. Food and Drug Administration and other medications that have been used for weight loss. DATA SOURCES Electronic databases, experts in the field, and unpublished ...

BACKGROUND Flibanserin, a 5-HT1A agonist and 5-HT2A antagonist, is indicated for the treatment of acquired, generalized hypoactive sexual desire disorder (HSDD) in premenopausal women. This post hoc analysis evaluated the effect of flibanserin treatment on body weight in premenopausal and postmenopausal women with HSDD. MATERIALS AND METHODS This analysis included three 24-week, double-blind,...

BACKGROUND Studies suggest that antipsychotic-induced weight gain is not a great concern in the elderly population. This study investigated the weight change in elderly patients with various treatment duration and antipsychotics. Part 1 of the study was to determine whether atypical antipsychotics induced weight change in elderly patients. Part 2 was to determine whether certain atypical antips...

Two experiments were conducted to examine the effects of prenatal stunting on skeletal muscle and adipose tissue cellularity in swine at 96 and 109 kg live weight. Animals used in Exp. 1 were large (1.56 kg average birth weight) and runt (.97 kg) littermate pigs and pigs with very low birth weight (.79 kg). The pigs with very low birth weight were half sibs to the large and runt littermates. Pi...

Ninety-three crossbred steer calves (BW+/-SD=385+/-50 kg) were used (n=48 steers in yr 1, n=45 steers in yr 2) to examine the relationship among carcass traits, lean, bone, and fat proportions, visceral tissue weights, and pancreatic digestive enzyme activity with DMI, ADG, G:F, and residual feed intake. Calves were progeny from crossbred dams predominantly of Angus and Simmental breeding and w...

1. The rate of utilization (k) of labelled thyroxine increased when energy intake, given as standard pig meal, was doubled from 20 to 40 g/kg body-weight per d. When the bulk of food was increased, but not its energy content, the value of k did not change. Ambient temperature was constant throughout the experiment. 2. Groups of pigs were given pig meal at 20 g/kg body-weight, 40 g/kg body-weigh...

Parabens are alkyl ester compounds of p-hydroxy benzoic acid and are widely used as preservatives in many pharmaceuticals and personal care products (PPCP), foodstuffs etc. Four parabens methyparaben, ethylparaben, propylparaben and butylparaben are found to be most widely used parabens in products of daily human use. Butylparaben is found to show stronger estrogenic response compared to rest o...