Severe cutaneous adverse drug reaction (SCAR) is considered to be a multifactorial drug side effect. This study was designed to investigate the epidemiology and human leukocyte antigen (HLA)-A and -B gene polymorphisms in pediatric patients with SCAR admitted in tertiary referral center, southwestern of Iran from 2013 to 2017. Demographic data, past allergy and autoimmune history, clinical pres...

In this paper, we present a low power high temperature 80C51 microcontroller. The low power optimizations are applied at gate and architectural level, by using extensive clock and data gating, and by completely redesigning the micro-architecture. We also present original clock gating techniques: pre-computed clock gating. To validate these techniques, extensive comparisons with other realizatio...

0360-8352/$ see front matter 2013 Elsevier Ltd. All rights reserved. http://dx.doi.org/10.1016/j.cie.2013.12.005 ⇑ Corresponding author. Tel.: 98 (0)21 8752 4022; fax: +98 (0)21 8851 2596. E-mail addresses: [email protected], [email protected] (R.Z. Farahani), [email protected] (M. Hekmatfar). 1 Tel.: +44 (0)20 8417 5098; fax: +44 (0)20 8417 7026. Reza Zanjirani F...

In this paper we present a variation of the template attack classification process that can be applied to block ciphers when the plaintext and ciphertext used are unknown. In a näıve implementation this attack can be applied to any round of a block cipher. We also show that when a block cipher is implemented with the masking countermeasure a similar attack can be applied to the first round of t...

1 Department of Drug Science and Technology, University of Turin, via Pietro Giuria 9, 10125 Torino, Italy 2 Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences and the National Institute of Biotechnology in the Negev, Ben-Gurion University of the Negev, 84103 Beer-Sheva, Israel 3 Division of Paediatric Endocrinology and Diabetology, University Children’s Hospital, ...

Microcytosis is a common hematological finding, usually related to iron deficiency or beta-thalassemia. When both of these conditions are excluded, alpha-thalassemia must be considered in the differential diagnosis. No simple biochemical test is able to diagnose the alpha-thalassemia trait. Using PCR amplification of the breakpoint in deletional forms, and amplification of the alpha 2 gene and ...

We studied the utility of pancreatic magnetic resonance imaging (MRI) in 72 thalassemia major patients (21 diabetic, 51 normoglycemic). Diabetic patients were significantly older (p<0.0001) and had smaller pancreas volume (p<0.0001). The two groups were comparable for ferritin and MRI-T2* heart, liver and pancreas. Pancreatic T2* signals were abnormal in 80% of both groups, and correlated with ...

We recently reported that glycated albumin (GA) is increased in subjects with longer duration of diabetes and with decreased insulin secretory function. Based on this, we investigated whether GA increases with time relative to glycated hemoglobin (HbA1c) and the association between GA and beta-cell function. We analyzed 340 type 2 diabetes patients whose serum GA and HbA1c levels had been repea...

OBJECTIVE To screen immediate family members of thalassaemia patients for carrier identification and counselling. METHODS The cross-sectional study was conducted at an urban thalassaemia treatment and prevention centre in Karachi, Pakistan, from January to December 2008, and involved 188 siblings of 100 thalassaemia patients. Complete blood count, including haemogram, was performed in the sib...