Objective: Cancer is one of the major causes of death worldwide irrespective of the sex. The aim of the study was to design, synthesize, and identification of novel anti-proliferative agents that can potently target cancer. Methods: We are reporting the synthesis of the new series of N-substituted 2-(2-butyl-4-chloro-1H-imidazole-5-yl)-1H-benzo[d]imidazole derivatives and evaluated for their an...

Chiral coordination polymers have attracted much attention due to their special properties and significant applications. In this work, we synthesized two non-centrosymmetric ligands, N,N-bis(4-(1H-imidazol-1-yl)phenyl)-4-(pyridin-4-yl)aniline (DIMPPA) and N-(4-(1H-imidazol-1-yl)phenyl)-4-(pyridin-4-yl)-N-(4-(pyridin-4-yl)phenyl)aniline (MIDPPA), via structural modification of two reported centr...

Five new iron(III) 1-hexene polymerisation catalysts were prepared from the reactions of 2,4-di-tert-butyl-6-(2-(1H-imidazol-4-yl)ethylimino)methylphenol (L1), or 4-tert-butyl-6-(2-(1Himidazol-4-yl)ethylimino)methylphenol (L2) or 2,4-di-tert-butyl-6-[(2-pyridin-2-yl-ethylimino)methyl-phenol (L3) with anhydrous iron(II) halides to form [FeCl2(L1)] (1), [FeBr2(L1)] (2), [FeI2(L1)] (3), [FeBr2(L2)...

A series of derivatives (E)-6-chloro-5-fluoro-2-styryl-1H-benzo[d]imidazole, and 5-fluoro-2-methylN-phenyl-1H-benzo[d]imidazol-6-amine was synthesized. Compounds confirmed by melting point, FT-IR, 1HNMR, Mass spectral analytical techniques predicted for their ADME, Pharmacokinetic properties.Synthesized compounds screened better antibacterial antiinflammatory activity. To synthesize a novel tri...

In the mol-ecule of the title compound, C7H9N3O3, the nitro and carbonyl groups are tilted with respect to the imidazole ring by 9.16 (6) and 65.47 (7)°, respectively. Neighbouring chains are linked via C-H⋯N and C-H⋯O hydrogen bonds forming two-dimensional slab-like networks lying parallel to (01-1).

IN THE CRYSTAL STRUCTURE OF THE TITLE COMPOUND [SYSTEMATIC NAME: 1-(2-hy-droxy-eth-yl)-2-methyl-5-nitro-1H-imidazol-3-ium perchlorate], C(6)H(10)N(3)O(3) (+)·ClO(4) (-), the cations are linked by inter-molecular N-H⋯O hydrogen bonds into zigzag chains along the c axis. The cations and anions are connected by O-H⋯O and C-H⋯O hydrogen bonds. A weak intra-molecular C-H⋯O hydrogen bond is also obse...