MicroRNAs have been confirmed to be a group of important regulators during the pathogenesis of nasopharyngeal carcinoma (NPC). This study confirmed that the expression of microRNA-92a (miR-92a) was significantly upregulated in NPC as compared to noncancerous nasopharyngeal epithelial tissues. Furthermore, high expression of miR-92a was observed in all NPC cell lines, especially in high metastat...

I ntravascular ultrasound is a new technique that allows intraluminal catheter-based vascular imaging. Technological advances in miniaturization have produced 4F to 8F catheters that can be safely maneuvered within coronary and peripheral arteries.1,2 Images obtained provide accurate measurements of lumen area as well as high-resolution images of arterial wall components.3,4 Histopathological s...

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BACKGROUND Hypoxic tumor cells can reduce the efficacy of radiation. Antiangiogenic therapy may transiently "normalize" the tumor vasculature to make it more efficient for oxygen delivery. The aim of this study is to investigate whether the recombinant human endostatin (endostar) can create a "vascular normalization window" to alleviate hypoxia and enhance the inhibitory effects of radiation th...

Nasopharyngeal carcinoma (NPC) shows the highest invasive and metastatic features among head and neck cancers. Distant metastasis remains the predominant mode of treatment failure in NPC patients. The role of interleukin-6 (IL-6) in NPC progression is not fully understood. In this study, we explored whether IL-6 could promote the migration and invasion activity of NPC cell lines, as well as whe...

In this paper, we obtain the general solution and the generalized Ulam-Hyers stability of the cubic and quartic functional equation 4(f(3x + y) + f(3x− y)) = −12(f(x + y) + f(x− y)) + 12(f(2x + y) + f(2x− y))− 8f(y)− 192f(x) + f(2y) + 30f(2x).

in this paper, we consider orthogonal stability of mixed type additive and cubic functional equation of the form $$f(2x+y)+f(2x-y)-f(4x)=2f (x+y)+2f(x-y)-8f(2x) +10f(x)-2f(-x),$$ with $xbot y$, where $bot$  is orthogonality in the sense of ratz.

We have prepared and studied a series of new brassinosteroid derivatives with a p-substituted phenyl group in the side chain. To obtain the best comparison between molecular docking and biological activities both types of brassinosteroids were synthesized; 6-ketones, 10 examples, and B-lactones, 8 examples. The phenyl group was introduced into the steroid skeleton by Horner-Wadsworth-Emmons. Th...