This essay looks at the historical significance of three APS classic papers that are freely available online: Hammel HT, Hardy JD, and Fusco MM. Thermoregulatory responses to hypothalamic cooling in unanesthetized dogs. Am J Physiol 198: 481-486, 1960 (http://ajplegacy.physiology.org/cgi/reprint/198/3/481). Hammel HT, Jackson DC, Stolwijk JAJ, Hardy JD, and Stromme SB. Temperature regulation by...

يعد النشاط الاقتصادي عصب الحياة وأساس قيام الدول واستمرارها، فهو الموجه الرئيسي لها، ومن خلاله تقاس مكانتها ، ونظرا للدور المهم الذي لعبه هذا الجانب في نشأة وتطور موانئ المغرب الأوسط، جاءت هذه الدراسة الموسومة أثر العلاقات التجارية ازدهار لموانئ الأوسط خلال المدة (ق 5-7هـ/11-13م)، والتي تتضمن مبحثين تناول المبحث الأول منها مع بلدان العالم الاسلامي، إضافة الى الحديث عن أهم السلع والبضائع المتباد...

The lantibiotic lacticin 481 is synthesized on ribosomes as a prepeptide (LctA) and posttranslationally modified to its mature form. These modifications include dehydration of serines and threonines, followed by intramolecular addition of cysteines to the unsaturated amino acids, which generates cyclic thioethers. This process breaks eight chemical bonds and forms six newbonds and is catalyzed ...

PAGE The problem.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 481 Material and methods . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 482 Genetic studies of crossing over. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 485 Cytological observations. . . . . . . . ....

Prothrombin (FII) is activated to α-thrombin (IIa) by prothrombinase. Prothrombinase is composed of a catalytic subunit, factor Xa (fXa), and a regulatory subunit, factor Va (fVa), assembled on a membrane surface in the presence of divalent metal ions. We constructed, expressed, and purified several mutated recombinant FII (rFII) molecules within the previously determined fVa-dependent binding ...

Penelitian ini memfokuskan pada kemampuan Masayarakat Banyumas dalam mengucapkan huruf-huruf Bahasa Arab ketika mereka belajar alquran. Jenis penelitian yang digunakan adalah deskriptif kualitatif dengan model studi kasus. Objek dikaji huruf sedangkan subjek terdiri dari jamaah pengajian dan pengajar alquran di masjid tempat penelitian. Teknik pengumpulan data wawancara, observasi, dokumentasi....

Kaposi's sarcoma-associated herpesvirus (KSHV) contains several open reading frames (ORFs) encoding proteins capable of initiating signal transduction pathways. Among them is the K15 ORF, which consists of eight exons encoding a protein with 12 predicted transmembrane domains and a cytoplasmic C terminus. When transiently expressed, the 8-exon K15 transcript gives rise to a protein with an appa...