A defi ning moment in the global AIDS response has been reached. The discourse is no longer about HIV prevention or HIV treatment; it is now about HIV control through the implementation of antiretrovirals as key components of combination interventions. Barely a year ago, visions of HIV control would have been considered far-fetched. The impetus for this change in mindset, which has been buildin...

TGF-beta is supposed to be the major cytokine responsible for post-radiation fibrosis of healthy tissues and actively modifies post-radiation changes. The growth of TGF-beta level induces the expression of collagen synthesis gene which triggers off the production of fibrosis of hyaline membranes. The main purpose of this study was to discover the way and methods of reducing post-radiation damag...

In metastatic ovarian cancer, resistance to platinum chemotherapy is common. Although the orphan nuclear receptor TR3 (nur77/NR4A1) is implicated in mediating chemotherapy-induced apoptosis in cancer cells, its role in ovarian cancer has not been determined. In an ovarian cancer tissue microarray, TR3 protein expression was elevated in stage I tumors, but downregulated in a significant subset o...

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Coronavirus disease 2019 (COVID-19) has significantly affected gastrointestinal (GI) endoscopy, with jurisdictions reporting up to a 95% reduction in procedure volumes compared before the pandemic.1Rutter MD et al. Gut [published online July 20, 2020]. https://doi.org/10.1136/gutjnl-2020-322179.Google Scholar In Ontario, Canada, large volume of colonoscopies not performed during first wave pand...

In this paper, the authors discuss security issues for cloud computing and present a layered framework for secure clouds and then focus on two of the layers, i.e., the storage layer and the data layer. In particular, the authors discuss a scheme for secure third party publications of documents in a cloud. Next, the paper will converse secure federated query processing with map Reduce and Hadoop...

In the quest of finding the ideal polymer optical fiber (POF) for Bragg grating sensing, we have fabricated and characterized an endlessly single mode microstructured POF (mPOF). This fiber is made from cyclo-olefin homopolymer Zeonex grade 480R which has a very high glass transition temperature of 138 °C and is humidity insensitive. It represents a significant improvement with respect to the a...

Here we present the fabrication of a solid-core microstructured polymer optical fiber (mPOF) made of polycarbonate (PC), and report the first experimental demonstration of a fiber Bragg grating (FBG) written in a PC optical fiber. The PC used in this work has a glass transition temperature of 145°C. We also characterize the mPOF optically and mechanically, and further test the sensitivity of th...

In 2019, the American Academy of Ophthalmology (AAO) created Task Force on Myopia in recognition substantial global increases myopia prevalence and its associated complications. The Force, led by Richard L. Abbott, MD, Donald Tan, comprised recognized experts prevention treatment, public health from around world, organization representatives Family Physicians, Optometry, Pediatrics. Academy’s B...