Background: The ongoing Coronavirus-19 disease epidemic is a public health emergency of international concern which could pose challenge to psychological resilience. This mainly the case patients with rheumatic diseases (RD). Objectives: aim this study was establish prevalence psychiatric symptoms in RD and identify factors associated stress. Methods: A cross-sectional conducted among RD. They ...

Methods 47 (42 male, 42±8 years-old) consecutive patients (pts) with paroxysmal AF and indication to ablation were included. Exclusion criteria for CMR: non-sinus rhythm and general contra-indications. Before ablation all underwent CMR for left atrial angiography for CARTO mapping. Using CMR, the following variables were assessed: left ventricle (LV) and left atrium (LA) volumes and ejection fr...

AIMS To evaluate the effect of beta-blockers in children with long QT syndrome (LQTS) we reviewed the outcome of 122 patients (pts). METHODS LQTS was diagnosed in 24 neonates and in 98 pts aged 0.5-15 years. Diagnosis was made because of syncope in 51 pts, bradycardia in 10 neonates and family history in 61 pts. The longest QTc ranged from 400 to 700 ms. Thirteen pts had 2:1 atrioventricular ...

CRA1008 Background: Decision making on systemic treatment of women with metastatic breast cancer is based on features like estrogen receptor (ER), progesterone receptor (PgR), and HER2 status assessed on the primary tumor. We evaluated the concordance of receptor status between primary tumor and liver metastases (mts) and its impact on treatment choice. METHODS We retrospectively analyzed a d...

351 Background: Previously treated hepatic colorectal metastases (CRC) and advanced hepatocellular cancer (HCC) are tumor challenges frequently unresponsive to systemic chemotherapy (CT). We reviewed survival outcome in chemoresistant/high-risk patients following hepatic artery infusion (HAI) in 21 CRC pts, 10 HCC pts, and 6 miscellaneous metastatic cancers. METHODS Patient groups: 21 CRC pts...

BACKGROUND Post-thrombotic syndrome (PTS) is a chronic complication of deep venous thrombosis (DVT). OBJECTIVES To determine the risk of PTS after DVT and to assess risk factors for PTS. METHODS Patients were recruited from the Multiple Environmental and Genetic Assessment (MEGA) study of risk factors for venous thrombosis. Consecutive patients who suffered a first DVT of the leg were inclu...

Methods A retrospective chart review of PH pts (n=42) who underwent clinically indicated CMR were analyzed. Demographic data showed mean age 61 yrs; 26% male; 55% WHO group 1 21% group 2, 5% group 3, 14% group 4, 5% group 5. RV volumetric data were indexed to BSA, and along with RVIP LGE information, were correlated with major adverse clinical events (MACE) including hospitalization, death, ref...

The post-thrombotic syndrome (PTS) develops in up to one half of patients after symptomatic deep venous thrombosis (DVT) and is the most common complication of DVT. Typical features of PTS include chronic pain, swelling, heaviness, oedema and skin changes in the affected limb. In severe cases, venous ulcers may develop. The frequency of PTS is likely to be reduced by preventing DVT with the use...

Methods In 42 HLHS patients (6.0 ±2.3 yrs) and 14 healthy volunteers (6.8 ±3.9 yrs), MRI first-pass perfusion (0.03 mmol/kg Gd-DTPA; TR/TE/a=2.6/1.1/20°) and late gadolinium enhancement (LGE) imaging was performed using a 3 Tesla scanner (Philips Achieva). Quantitative myocardial blood flow at rest and stress (Adenosin 140 mcg/kg/min) was calculated in 4 anatomical RV segments per slice using a...

Post-traumatic seizures (PTS) are a significant complication from traumatic brain injury (TBI). Adenosine, a major neuroprotective and neuroinhibitory molecule, is important in experimental epilepsy models. Thus, we investigated the adenosine A1 receptor (A1AR) gene and linked it with clinical data extracted for 206 subjects with severe TBI. Tagging SNPs rs3766553, rs903361, rs10920573, rs67017...