Muscará, Marcelo N., and John L. Wallace. Nitric Oxide. V. Therapeutic potential of nitric oxide donors and inhibitors. Am. J. Physiol. 276 (Gastrointest. Liver Physiol. 39): G1313–G1316, 1999.—Nitric oxide is a crucial mediator of gastrointestinal mucosal defense, but, paradoxically, it also contributes to mucosal injury in several situations. Inhibitors of nitric oxide synthesis and compounds...

Coopersmith, Craig M., David O’Donnell, and Jeffrey I. Gordon. Bcl-2 inhibits ischemia-reperfusion-induced apoptosis in the intestinal epithelium of transgenic mice. Am. J. Physiol. 276 (Gastrointest. Liver Physiol. 39): G677–G686, 1999.—Little is known about the effects of ischemia-reperfusion on the inductive, commitment, or execution phases of apoptosis. We have created a genetically defined...

HANS BARLE,1 PIA ESSÉN,1 BJÖRN NYBERG,2 HANS OLIVECRONA,2 MICHAEL TALLY,3 MARGARET A. MCNURLAN,4 JAN WERNERMAN,1 AND PETER J. GARLICK4 1Department of Anesthesiology and Intensive Care and 2Department of Surgery, Huddinge University Hospital, S-141 86 Huddinge; 3Department of Endocrinology, Karolinska Hospital, S-104 01 Stockholm, Sweden; and 4Department of Surgery, University Medical Center, St...

Gupta, Sanjeev, Pankaj Rajvanshi, Emma Aragona, Chang-Don Lee, Purnachandra R. Yerneni, and Robert D. Burk. Transplanted hepatocytes proliferate differently after CCl4 treatment and hepatocyte growth factor infusion. Am. J. Physiol. 276 (Gastrointest. Liver Physiol. 39): G629– G638, 1999.—To understand regulation of transplanted hepatocyte proliferation in the normal liver, we used genetically ...

The global food system makes a significant contribution to climate changing greenhouse gas emissions with all stages in the supply chain, from agricultural production through processing, distribution, retailing, home food preparation and waste, playing a part. It also gives rise to other major environmental impacts, including biodiversity loss and water extraction and pollution. Policy makers a...

Ghigo, E., G. Aimaretti, M. Maccario, G. Fanciulli, E. Arvat, F. Minuto, G. Giordano, G. Delitala, and F. Camanni. Dose-response study of GH effects on circulating IGF-I and IGFBP-3 levels in healthy young men and women. Am. J. Physiol. 276 (Endocrinol. Metab. 39): E1009–E1013, 1999.—The aim of our study was to define the dose-response effect of a short-term treatment with different recombinant...

Carroll, Robert E., Kristina A. Matkowskyj, Subrata Chakrabarti, Thomas J. McDonald, and Richard V. Benya. Aberrant expression of gastrin-releasing peptide and its receptor by well-differentiated colon cancers in humans. Am. J. Physiol. 276 (Gastrointest. Liver Physiol. 39): G655– G665, 1999.—Epithelial cells lining the adult human colon do not normally express gastrin-releasing peptide (GRP) o...

Objective. The relationship between sleep quality and pain has been studied in populations with chronic pain and in nonclinical populations using experimental paradigms. Little is known about the familial contributions to this relationship. This study examines self-reported sleep quality and pain in a nonclinical sample and to explore familial (i.e., shared genetic and common family environment...

Shangraw, Robert E., and Farook Jahoor. Effect of liver disease and transplantation on urea synthesis in humans: relationship to acid-base status. Am. J. Physiol. 276 (Gastrointest. Liver Physiol. 39): G1145–G1152, 1999.—It has been suggested that hepatic urea synthesis, which consumes HCO3 , plays an important role in acid-base homeostasis. This study measured urea synthesis rate (Ra urea) dir...