نتایج جستجو برای: 38
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The deleterious effects of a disrupted copper metabolism are illustrated by hereditary diseases caused by mutations in the genes coding for the copper transporters ATP7A and ATP7B. Menkes disease, involving ATP7A, is a fatal neurodegenerative disorder of copper deficiency. Mutations in ATP7B lead to Wilson disease, which is characterized by a predominantly hepatic copper accumulation. The low i...
Dr. Leigh H. Simmons: An 87-year-old man with multiple chronic medical problems was seen in an outpatient clinic of this hospital because of sore throat and fatigue. The patient had been in his usual health until several weeks before presentation, when hoarseness, sore throat, and increasing fatigue developed. At the urging of his family, he was seen by his physician in an outpatient clinic of ...
The new rural development paradigm was developed as a response to the inefficiency of the old development model. The expansion of the EU to the Mediterranean countries (Greece 1981, Portugal and Spain 1986) has pointed out large regional disparities, especially in rural regions. Thus, common agricultural policy was developed between 1957 and 1962 when it finally came into force in the EU. The a...
This case report describes a 48-year-old female who presented with complaints of right shoulder pain, hyperesthesias and swelling of the hand along with added symptoms of pain centralization following a cerebrovascular accident. On clinical evaluation, the patient satisfied the Budapest diagnostic criteria for Complex Regional Pain Syndrome (CRPS) type-1. Physical therapy management (1st three ...
Short Messaging Service (SMS) text reminders provide a promising approach for increasing medication adherence. This review evaluates the literature from randomized controlled studies, observational studies as well as qualitative studies pertaining to efficacy of SMS reminders for improving the medication adherence. SMS interventions have been studied for a variety of disorders from medical and ...
38 UITF abstract 38 Accounting for ESOP trusts (Issued 15 December 2003) Introduction This Abstract supersedes UITF Abstract 13 ‘Accounting for ESOP trusts’ (issued on 8 June 1995). Abstract 13 addressed: (a) the nature and extent of the sponsoring company’s assets and liabilities that should be recognised under employee share ownership plans (ESOPs); and (b) the timing of expense recognition u...
b-Glucan is one of the most abundant polysaccharides in fungal pathogens, yet its importance in antifungal immunity is unclear. Here we show that deficiency of dectin-1, the myeloid receptor for b-glucan, rendered mice susceptible to infection with Candida albicans. Dectin-1-deficient leukocytes demonstrated significantly impaired responses to fungi even in the presence of opsonins. Impaired le...
Any software development project uses software tools that assist its developers in coordinating their efforts. These tools, termed coordination technologies in this paper, have undergone remarkable changes over time in the functionality that they offer. We contribute a novel perspective on this historical trend with our Coordination Pyramid, a framework that recognizes four distinct paradigms o...
B. D. Anderson, 1 A. R. Baldwin, 1 P. Baumann, 2 B. A. Brown, 3 F. Didierjean, 2,* C. C. Foster, 4 L. A. C. Garcia, 1,† A. Huck, 2 A. Knipper, 2 R. Madey, 1,5 D. M. Manley, 1 G. Marguier, 6 M. Ramdhane, 2,‡ H. Ravn, 7 C. Richard-Serre, 8 G. Walter, 2 and J. W. Watson 1 Department of Physics and Center for Nuclear Research, Kent State University, Kent, Ohio 44242 Centre de Recherches Nucléaires,...
There has been much recent discussion ahout the ultimate sources of macroeconomic variability. A number ofauthors attribute most of this variability to only B few sowces, sometimes only one. Although there may be only B few important sources, this is fsr from obvious, since economies seem compliested. The purpose of this paper is to provide qusntitstive estimates of various sowces of vsriabilit...
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