We reported previously that three basic amino acids (Arg-360, Arg-364 and Lys-372) of DnaA protein are essential for its functional interaction with cardiolipin. In this study, we examined the effect of mutation of some basic amino acids in a potential amphipathic helix (from Lys-327 to Ile-345) of DnaA protein on this interaction. ATP binding to the mutant DnaA protein, in which Arg-328, Arg-3...

DnaA protein, the initiator of chromosomal DNA replication in Escherichia coli, seems to be regulated through its binding to acidic phospholipids, such as cardiolipin. In our previous paper (Hase, M., Yoshimi, T., Ishikawa, Y., Ohba, A., Guo, L., Mima, S., Makise, M., Yamaguchi, Y., Tsuchiya, T., and Mizushima, T. (1998) J. Biol. Chem. 273, 28651-28656), we found that mutant DnaA protein (DnaA4...

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 365 1. Evidence of Cardiac Fatigue . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 367 1.1 During Prolonged Exercise . . . . . . . . . . . . . . . . . . . ...

VI. VII. VIII. I X . X. Thc Plants . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 372 Thc I tcrhivores . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 373 FwdinK Specificity of Marine versus Terrestrial llerbivores . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 375 (;raring Rates and Selection ...

The method introduced in a previous paper to simplify the tensorial reduction in multi-leg loop calculations is extended to generic one-loop integrals, with arbitrary internal masses and external momenta. CERN-TH/97-372 December 1997

may make it a more appropriate agent for testing the vasodilator response. Background – In patients with primary (Thorax 1997;52:369–372) pulmonary hypertension who respond to vasodilators acutely, survival can be im

Correspondence Z. A. Efstathiadou, PhD Consultant Endocrinologist Department of Endocrinology “Hippokration” General Hospital of Thessaloniki Konstantinoupoleos 49 54642 Thessaloniki Greece Tel.: + 30/231/3312 269 Fax: + 30/231/0532 372 [email protected]

s Abstracts of posters presented at ‘Northern Exposure’ annual scientific meeting of the British Branch of the International League against Epilepsy, Edinburgh, March 30th–April 1st, 2000 356 Correspondence Letter to the Editor R. Dasheiff 372