The first examples of a Pd-catalyzed carbonylation of aryl boronic acids with sp(3) carbon partners are presented. Various boronic acids were shown to react with 1,3-diesters and 1,3-diketones to afford structurally unique carbonyl compounds. By employing 2-substituted 1,3-diesters, synthetically-challenging quaternary carbon centres were accessed. In total, 42 examples of aryl carbonyl compoun...

1,2-Diketones have been reacted in one-pot method with 1,2-diamines at room temperature with ZnO nanoparticles as a catalyst. ZnO nanoparticles as an available and reusable catalyst is used for the synthesis of Quinoxalinein improved yields.

Recently described scientific literature has identified the airborne presence of 2,3-butanedione (diacetyl) and 2,3-pentanedione at concentrations approaching or potentially exceeding the current American Conference of Industrial Hygienists' (ACGIH) Threshold Limit Values (TLVs) at commercial coffee roasting and production facilities. Newly established National Institutes of Occupational Safety...

A simple, chemoselective transfer hydrogenation of aryl aldehydes with the aid of Amberlite((R)) resin formate (ARF), a stable H-donor, in the presence of catalytic ruthenium trichloride is described. Aromatic aldehydes and 1,2-diketones are reduced efficiently and selectively, while aryl ketones remain unchanged. Several other potentially reducible groups attached to the aromatic moiety are un...

Poly(ADP-ribose)polymerase-1 (PARP-1) is an important target for drug design for several therapeutic applications. 5-Aminoisoquinolin-1-one (5-AIQ) is a highly water-soluble lead compound; synthetic routes to 3-substituted analogues were explored. Tandem Hurtley coupling of β-diketones with 2-bromo-3-nitrobenzoic acid, retro-Claisen acyl cleavage and cyclisation gave the corresponding 3-substit...

Silica supported phosphorus pentoxide (P2O5·SiO2) is an efficient catalyst for synthesis of 1,3,5-substituted pyrazoles via the condensation of 1,3-diketones and hydrazines. Simplicity of procedure, mild condition, being solvent-free, high yields, and easy workup are some advantages of this protocol.

in present paper a simple procedure for the synthesis of enaminones without catalyst from 1,3-diketones that reacted with primary or secondary amines in ethanol as solvent, as well as the reaction of enaminones with unsaturated esters such as dimethyl acetylene dicarboxylate are reported.

Cuticular wax composition greatly impacts plant responses to dehydration. Two parallel pathways exist in Triticeae for manipulating wax composition: the acyl elongation, reduction, and decarbonylation pathway that is active at the vegetative stage and yields primary alcohols and alkanes, and the β-diketone pathway that predominates at the reproductive stage and synthesizes β-diketones. Variatio...