Introduction: Electronic portal imaging devices (EPIDs) could potentially be useful for intensity-modulated radiation therapy (IMRT) and VMAT QA. The data density, high resolution, large active area, and efficiency of the MV EPID make it an attractive option. However, EPIDs were designed as imaging devices, not dosimeters, and as a result they do not inherently measure dose in ...

background: aim of this study is to evaluate the accuracy of the gated volumetric modulated arc therapy (vmat/rapidarc) using 2d planar dosimetry, dynalog files and compass 3d dosimetry system. materials and methods: pre-treatment quality assurance of 10 gated vmat plans was verified using 2d array and compass 3d dosimetry system. advantage of compass over 2d planar is that it provides the clin...

Most previous studies on visual saliency have only focused on static or dynamic 2D scenes. Since the human visual system has evolved predominantly in natural three dimensional environments, it is important to study whether and how depth information influences visual saliency. In this work, we first collect a large human eye fixation database compiled from a pool of 600 2D-vs-3D image pairs view...

Three-dimensional (3D) culture models represent a better approximation of solid tumor tissue architecture, especially cell adhesion, in vivo than two-dimensional (2D) cultures do. Here, we explored the role of architecture in chemosensitivity to platinum in colon cancer. Under the 3D culture condition, colon cancer cells formed multicellular spheroids, consisting of layers of cells. 3D cultures...

The critical role of migration and invasion in cancer metastasis warrants new therapeutic approaches targeting the machinery regulating cell migration and invasion. While 2-dimensional (2D) models have helped identify a range of adhesion molecules, cytoskeletal components and regulators that are potentially important for cell migration, the use of models that better mimic the 3-dimensional (3D)...