نتایج جستجو برای: 25oh vitamin d3

تعداد نتایج: 104804  

Journal: :Turkish journal of medical sciences 2016
Said Said Elshama Hosam-Eldin Hussein Osman Ayman El-Meghawry El-Kenawy Hamdi Mohamed Youseef

BACKGROUND/AIM Vitamin D3 has increased risk of toxicity due to its common use in multivitamin preparations. Vitamin K and vitamin A play an important role in vitamin D action. The goal of the current study was to compare the protective effects of vitamin K and vitamin A on the modulation of hypervitaminosis D3 toxicity in rats by assessing serum calcium, renal function tests, cardiac enzymes, ...

2016
J. C. Han G. H. Chen J. G. Wang J. L. Zhang H. X. Qu C. M. Zhang Y. F. Yan Y. H. Cheng

This study was conducted to evaluate the relative bioavailability (RBV) of 25-hydroxycholecalciferol (25-OH-D3) to cholecalciferol (vitamin D3) in 1- to 21-d-old broiler chickens fed with calcium (Ca)- and phosphorus (P)-deficient diets. On the day of hatch, 450 female Ross 308 broiler chickens were assigned to nine treatments, with five replicates of ten birds each. The basal diet contained 0....

2011
Sophia L. Maund Wendy W. Barclay Laura D. Hover Linara S. Axanova Guangchao Sui Jason D. Hipp James C. Fleet Andrew Thorburn Scott D. Cramer

Vitamin D3 is a promising preventative and therapeutic agent for prostate cancer, but its implementation is hampered by a lack of understanding about its mechanism of action. Upon treatment with 1a,25-dihydroxyvitamin D3 [1,25(OH)2D3, vitamin D3], the metabolically active form of vitamin D3, adult prostate progenitor/ stem cells (PrP/SC) undergo cell-cycle arrest, senescence, and differentiatio...

2017
Jagrati Mathur Soe Naing Paul Mills David Limsui

AIM To prospectively evaluate the effects of vitamin D3 on disease activity and quality of life in ulcerative colitis (UC) patients with hypovitaminosis D. METHODS The study was a prospective double-blinded, randomized trial conducted at Community Regional Medical Center, Fresno, CA from 2012-2013. Patients with UC and a serum 25(OH)D level <30 ng/ml were eligible for the study. Enrolled subj...

Fahimeh Lavi Arab, Fatemeh Faraji, Mahmoud Mahmoudi, Mahmoudreza Kalantari Maryam Rastin, Nafise Tabasi Shahrzad Zamani Taghizadeh Rabe

Objective(s): Systemic lupus erythematosus (SLE) is a multi-factorial autoimmune disease which may be characterized by T lymphocytes dysfunctions. Th17 cells have been identified as new effector cells, which play an important role in the pathogenesis. In recent years, immunomodulatory effect of vitamin D3 has been noticed. In the present experiment, the effect of vitamin D3 on the expression of...

11, 25 dihydroxy vitamin D3, an active metabolite of vitamin&shy;D3 has been reported to inhibit the growth of number neoplasms such as prostate, breast, colorectal, leukemia and skin cancers. Valproic acid, as a potent histone deacetylase inhibitor, also plays an important role in inhibition of proliferation of tumor cells. However, there are no reports so far on the cooperation between valpro...

2013
Yasuteru Kondo Takanobu Kato Osamu Kimura Tomoaki Iwata Masashi Ninomiya Eiji Kakazu Masahito Miura Takehiro Akahane Yutaka Miyazaki Tomoo Kobayashi Motoyasu Ishii Norihiro Kisara Kumiko Sasaki Haruo Nakayama Takehiko Igarashi Noriyuki Obara Yoshiyuki Ueno Tatsuki Morosawa Tooru Shimosegawa

OBJECTIVE 1,25(OH)2 vitamin D3 can affect immune cells. However, the mechanism responsible for the favorable effects of 1(OH) vitamin D3, which becomes 1,25(OH)2 vitamin D3 in the liver, is not clear. The aim of this study is to analyze the immunological response of 1(OH) vitamin D3 supplementation in CH-C patients. DESIGN Forty-two CH-C patients were treated with 1(OH) vitamin D3/Peg-IFNα/RB...

Objective(s):Multiple sclerosis (MS) is a demyelinating disease. The prevalence of MS is highest where environmental supplies of vitamin D are low. Cognitive deficits have been observed in patients with MS. Oxidative damage may contribute to the formation of MS lesions. Considering the involvement of hippocampus in MS, an attempt is made in this study to investigate the effects of vitamin D3 on...

2017
Luis G Vargas Buonfiglio Marlene Cano Alejandro A Pezzulo Oriana G Vanegas Calderon Joseph Zabner Alicia K Gerke Alejandro P Comellas

INTRODUCTION Vitamin D3 supplementation has been reported to prevent lung infections and increase the gene expression of antimicrobial peptides such as cathelicidin. We investigated the effect of vitamin D3 supplementation on the antimicrobial activity of airway surface liquid (ASL) in human subjects. Since smoking can increase the risk of respiratory infections, we also investigated the effect...

Journal: :Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2007
Andrzej Kraśniak Maciej Drozdz Mieczysław Pasowicz Grzegorz Chmiel Martyna Michałek Dorota Szumilak Piotr Podolec Piotr Klimeczek Małgorzata Konieczyńska Ewa Wicher-Muniak Wiesława Tracz Thao N'guyen Khoa Jean-Claude Souberbielle Tilman B Drueke Władysław Sulowicz

BACKGROUND Atherosclerosis and vascular calcifications are common causes of morbidity and mortality in maintenance haemodialysis patients. In addition to the well-known traditional risk factors, uraemia-specific factors appear to enhance dramatically the progression of the pathological processes involved. The aim of the present study was to evaluate the degree of atherosclerosis and vascular ca...

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