BACKGROUND Acute respiratory tract infections (ARI) are the leading cause of morbidity and mortality in developing countries, especially in Africa. This study sought to determine whether human coronaviruses (HCoVs) are associated with upper respiratory tract infections among older children and adults in Ghana. METHODS We conducted a case control study among older children and adults in three ...

Five new triterpenoid saponins, heinsiagenin A 3-O-[α-l-rhamnopyranosyl-(1→2)-β-d-glucopyranosyl-(1→2)]-β-d-glucopyranoside (1), heinsiagenin A 3-O-[α-l-rhamnopyranosyl-(1→2)-β-d-glucopyranosyl-(1→2)]-[β-d-glucopyranosyl-(1→4)]-β-d-glucopyranoside (2), 2α-hydroxyheinsiagenin A 3-O-[α-l-rhamnopyranosyl-(1→2)-β-d-glucopyranosyl-(1→2)]-β-d-glucopyranoside (3), 2α-hydroxyheinsiagenin A 3-O-[β-d-glu...

In the present study a various phytochemical compounds that have been isolated from Melia azedarach and showed phytoconstituents leaves against three of pathogenic fungi are as follows: Alternaria alternate, Neoscytalidium dimidiatum Sordaria fimicola. ''The Phytochemical M. were exposed to (GC-MS) analysis. The results highest activity reviewed fungal, (Alternaria fimicola). All concentrations...

We consider the following family of random trigonometric polynomials form Sn(θ):=1 n ∑k=1nakcos(kθ)+bksin(kθ), where variables {ak,bk}k≥1 are i.i.d. and symmetric, defined on a common probability space (Ω,F,P). In seminal paper [SZ54], Salem Zygmund proved that for Rademacher coefficients, P−almost surely all t∈R limn→+∞ 1 2π∫02πeitSn(θ)dθ=e−t2∕2. To best our knowledge, natural question fluctua...

Introduction of neomycin-resistance into a marine-derived, wild-type Penicillium purpurogenum G59 resulted in activation of silent biosynthetic pathways for the secondary metabolite production. Upon treatment of G59 spores with neomycin and dimethyl sulfoxide (DMSO), a total of 56 mutants were obtained by single colony isolation. The acquired resistance of mutants to neomycin was testified by t...

Although the quinoline ring is found in a wide variety of biologically active compounds and is frequently condensed with various heterocycles, synthesis and biological evaluation of the indenoquinoline skeleton attracts only very limited attention. We report herein the synthesis and antiproliferative evaluation of certain indeno[1,2-c]quinoline derivatives against the growth of six cancer cell ...