نتایج جستجو برای: 201

تعداد نتایج: 12397  

Journal: :European urology 2016
Christophe Massard Heidi M Penttinen Egils Vjaters Petri Bono Vilnis Lietuvietis Teuvo L Tammela Annamari Vuorela Pirjo Nykänen Pasi Pohjanjousi Amir Snapir Karim Fizazi

BACKGROUND ODM-201 is a novel second-generation androgen receptor inhibitor for the treatment of metastatic castration-resistant prostate cancer (mCRPC). OBJECTIVE To evaluate the pharmacokinetics of ODM-201 tablet products and preliminary long-term safety, tolerability, and antitumor activity of ODM-201 in chemotherapy-naive men with mCRPC. DESIGN, SETTING, AND PARTICIPANTS Thirty patients...

Journal: :Circulation 1975
H W Strauss K Harrison J K Langan E Lebowitz B Pitt

Following intravenous administration, the myocardial concentration of tracer thallium-201, potassium-43, and rubidium-81 were determined in mice; thallium was present in the greatest concentration in the myocardium (2.08% compared 1.25% for potassium and 1.15% for rubidium at 10 minutes). The regional myocardial distribution of thallium-201 was determined in dogs under conditions of normal flow...

2005
IAN K. BAILEY H. WILLIAM STRAUSS BERTRAM PITT

The sensitivity of myocardial perfusion imaging (MPI) using thallium-201 injected both at rest and during peak exercise was compared to simultaneously recorded 12 lead electrocardiography (ECG) for the detection of transient ischemia in 20 normal subjects and 63 patients with coronary artery disease (CAD). No significant perfusion defects or ECG changes were seen on either the rest or exercise ...

Journal: :Singapore medical journal 2004
Y H Chan

Correspondence to: Dr Y H Chan Tel: (65) 6325 7070 Fax: (65) 6324 2700 Email: chanyh@ cteru.com.sg In the 100 series(1-4) the common univariate techniques (summarized in Table I) available for data analyses were discussed. These techniques do not allow us to take into account the effect of other covariates/ confounders (except for partial correlation(4)) in an analysis. In such situations, a Re...

Journal: :Nuclear medicine and biology 2005
Yousuke Kanayama Shuichi Enomoto Toshiaki Irie Ryohei Amano

Following intranasal administration of radioactive (86)Rb(+) and (201)Tl(+) in mice, we observed this direct transport via the olfactory nerve pathway. The (86)RbCl and (201)TlCl solutions were administered to two groups of mice, the unilateral intranasal and intravenous administration groups. After sacrifice, their heads were divided into the right and left side, which were then subdivided int...

Journal: :Journal of neuroimmunology 2013
Arunakumar Gangaplara Chandirasegaran Massilamany David Steffen Jay Reddy

We report here identification of novel mimicry epitopes for interphotoreceptor retinoid-binding protein (IRBP) 201-216, a candidate ocular antigen that causes experimental autoimmune uveoretinitis (EAU) in A/J mice. One mimicry epitope from Ehrlichia canis (EHC), designated EHC 44-59, induced cross-reactive T cells for IRBP 201-216 capable of producing T helper (Th)1 and Th17 cytokines, but fai...

Journal: :Circulation 1990
B Pitt

T he use of vasodilator thallium-201 myocardial imaging, although still investigational, is finding wide application. The principle of vasodilator thallium-201 myocar-dial imaging was first put forward by Strauss and Pitt,' who used dimethyladenosine in dogs with experimental coronary artery narrowing. They demonstrated that dimethyladenosine increased coronary blood flow and thallium-201 uptak...

Journal: :British journal of anaesthesia 1998
T Standl M A Burmeister E P Horn S Wilhelm W T Knoefel J Schulte am Esch

We have studied the use of ultrapurified polymerized bovine haemoglobin (HBOC-201) in patients undergoing preoperative haemodilution before liver resection. After autologous blood donation of 1 litre, 12 patients (six males, six females, mean age 59 (35-69) yr) received Ringer's lactate solution 2 litre and, in a random design, 6% hydroxyethyl starch 70,000/0.5 (HES) 3 ml kg-1 or HBOC-201 0.4 g...

Journal: :Sarcoma 2002
P. Choong T. Kunisada G. Powell S. Schlict R. Hicks J. Slavin

Background: Cartilaginous tumours may present diagnostic and prognostic dilemmas. Heterogeneity of appearance and histology sometimes confound our ability to make accurate diagnoses of the state of malignancy and grade. Conventional methods that combine history, plain radiographs, and histology may result in both under and over treatment. A method, which allows preoperative assessment of malign...

Journal: :Circulation 1980
J Morrison J Coromilas D Munsey M Robbins M Zema S U Chiaramida P Reiser L Scherr

Creatine kinase-MB isoenzyme release (CK-MB-g-Eq) was correlated with left ventricular (LV) radionuclide gated blood pool wall motion estimates of percent abnormally contracting regions (%ACR), ejection fraction (EF) and quantitative thallium-201 (Tl-201) LV perfusion scintigraphy (Tl-201 perfusion index) during evolving myocardial infarction (MI). Of the 35 patients, 14 had no evidence of eith...

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