DEVELOPING a softwareintensive system is like raising a child. As Will PleasantRyan observed, both babies and code have smells, you get used to changing requirements, you have to take the long view, you can’t do it alone, and eventually you have to let go.1 I would add to Will’s most excellent simile that, although you might think you know everything up front, you certainly don’t, and therefore...

"Slime" played a brief and spectacular role in the 19th century founded by the theory of primordial slime by Ernst Haeckel. However, that substance was never found and eventually abandoned. Further scientific attention slowly began in the 1930s referring to slime as a microbial product and then was inspired by "How bacteria stick" by Costerton et al. in 1978, and the matrix material was conside...

The chapter begins by outlining key theoretical beliefs embodied in the psychological perspective that informs this work, then outlines what mental complexity might look like in the context of a senior public servant. Two key developmental pathologies are then described (over and under-differentiation) and linked to senior leadership in Australia by considering Judith Brett’s (2007) analysis of...

The covariance between nominal bonds and stocks has varied considerably over recent decades and has even switched sign. It has been predominantly positive in periods such as the late 1970’s and early 1980’s when the economy has experienced supply shocks and the central bank has lacked credibility. It has been predominantly negative in periods such as the 2000’s when investors have feared weak a...

Fluoroquinolones were discovered in the 1960s as a derivative of the antimalarial drug chloroquine. Over the past 40 years, many fluoroquinolones have been developed for use in human and veterinary medicine. As with all classes of antibiotics, resistance to fluoroquinolones is a serious concern, and multiple avenues for resistance are being investigated. Resistance-associated point mutations in...

The themes presented in this Presidential address are introduced through masterpieces of medicine in art from the very earliest depictions to the modern day. The representations of medicine in art provide a commentary on the place of medicine in society and how it was viewed by society. Some artists used their work both to highlight important health issues of the time and as a " propaganda " to...

My third year of medical school, and I have finally begun my training. I am slowly learning to be a surgeon. I will open you up and search through the detritus of sickness, extirpate what is necessary, and leave in my wake a health of my own creation. There is power in that; a power that I have already glimpsed. Reaching out and calmly saying, "knife." Deliberately moving the scalpel across the...