A family of anionic, formally nickel(0) complexes supported by bidentate NHC–pyridone ligands is described. The unsymmetric chelating environment and capping [K(18-crown-6)]+ countercation allow isolation single-component, monometallic in high yield. steric electronic properties are assessed through a battery experimental (NMR, IR, UV–vis, X-ray diffraction) computational tools. Catalytic activ...

In the title compound, C21H17N5O3S3·C3H7NO, the toluene-sulfonamide ring and the combined ring system involving the pyridone and benzo-thia-zole rings subtend an inter-planar angle of 39.86 (4)°. The pyridone and benzo-thiazyl rings are linked by the intra-molecular hydrogen bond N-Hamine⋯Nthia-zole. The DMF O atom accepts two classical hydrogen bonds. The mol-ecules are linked by hydrogen bond...

On crystallization from CHCl3, CCl4, CH2ClCH2Cl and CHCl2CHCl2, 6-chloro-5-hydroxy-2-pyridone, C5H4ClNO2, (I), undergoes a tautomeric rearrangement to 6-chloro-2,5-dihydroxypyridine, (II). The resulting crystals, viz. 6-chloro-2,5-dihydroxypyridine chloroform 0.125-solvate, C5H4ClNO(2).0.125CHCl3, (IIa), 6-chloro-2,5-dihydroxypyridine carbon tetrachloride 0.125-solvate, C5H4ClNO(2)..0.125CCl4, ...

A new method for the synthesis of β-iodo N-alkenyl 2-pyridones from substituted 2-propargyloxypyridines has been discovered . These compounds present a unique complement of orthogonal functionality and structural characteristics that are unavailable via other routes. The ready access to these compounds renders them an important entry point for the preparation of more complex N-alkyl pyridone-co...

Phytochemical study of the methanol extract of Mallotus anisopodus led to the isolation of two new megastigmane sulphonoglucosides, namely anisoposides A (1) and B (2), along with junipetrioloside A (3), bergenin (4), os-tocopherol, and N1-methyl-2-pyridone-5-carboxamide. Their structures were deduced by spectroscopic and spectrometric methods including 1D-, 2D-NMR, ESI-MS, and HRESI-MS.

After the oral administration of nicotinamide to human subjects, two ultraviolet-absorbing compounds have regularly been detected on chromatograms of plasma extracts. The less polar of these, named Compound Y, has been identified as N’-methyl2-pyridone-5-carboxamide (1). In the present communication, evidence is presented that the more polar metabolite, Compound X, is N’-methyl-4-pyridone-3-car...