O6-Ethylthioethyldeoxyguanosine has been synthesized from 6-chloro-3',5'-di-O-acetyldeoxyguanosine and characterized by UV, fluorescence, and mass spectrometry. High-pressure liquid chromatography studies have shown that this modified nucleoside is formed when the one-armed sulfur mustard, chloroethyl ethyl sulfide, reacts with deoxyguanosine. This result supports the hypothesis that the mutage...

Background: Numerous studies have been conducted on humans, animals, and cell cultures exposed to Sulfur Mustard (SM). However, the precise mechanism and cause or long-term pattern of SM injuries are not well defined. There is no protocol available for treating people with severe eye, lung, and skin ailments. The current study aimed to develop an animal model of the acute and delayed complicati...

O6-Ethylthioethyldeoxyguanosine has been synthesized from 6-chloro-3',5'-di-O-acetyldeoxyguanosine and characterized by UV, fluorescence, and mass spectrometry. High-pressure liquid chromatography studies have shown that this modified nucleoside is formed when the one-armed sulfur mustard, chloroethyl ethyl sulfide, reacts with deoxyguanosine. This result supports the hypothesis that the mutage...

In the production of biological effects such as vesication by bis-p-chloroethyl sulfide (mustard gas) it has been considered probable that inactivation of tissue enzymes is of foremost importance. In view of the reaction characteristics of bis-p-chloroethyl sulfide it has appeared likely that this inhibition is due to an alkylation reaction involving essential groups of the enzymes. Involvement...

In this research, CaO (calcium oxide) nanoparticles were synthesized by Co-Precipitation method in the absence and presence of Polyvinylpyrrolidone (PVP) via using calcium (II) nitrate. The Polyvinylpyrrolidone (PVP) was used as a capping agent to control the agglomeration of the nanoparticles. The synthesized samples were characterized via SEM, XRD and FTIR techniques. The average sizes of nan...

transmitted in any form or by any means without the prior permission in writing of the publisher nor be issued to the public or circulated in any form other than that in which it is published. In the UK there has historically been a clear demarcation between the academic and vocational routes through education post-16. Generally vocational study is taken either on a part time basis or full time...

This paper analyses the stock market linkages of the selected Central and Eastern European (CEE) markets (Czech Republic – PX, Hungary – BUX and Poland – WIG20) with the Western European stock market represented by the German DAX and studies also the comovement between the individual CEE countries’ stock markets. The dynamic conditional correlation (DCC) models were used to model the co-movemen...

The bifunctional sulphur mustard (bis-(2-chloroethyl)sulphide, HD) and its monofunctional analogue (2-chloroethyl ethyl sulphide, CEES) are both vesicants. In this study, both mustards were shown to rapidly alkylate the AP2 consensus binding sequence incorporated in a 26mer oligonucleotide. The reaction was essentially complete within 10 min under the conditions employed in this study and -95% ...

This paper investigates the motives and reasons behind the assistance programs to CEE countries from the perspective of the Swedish government, which was responsible for this kind of aid. How did Swedish government arrive at decisions regarding the technical assistance to CEE countries and changes therein? This paper is a follow-up on previous research by the authors on the Western assistance t...

Primary degree holders have extraordinarily low employment rates in Central and East European (CEE) countries, a bias that largely contributes to their low levels of aggregate employment. The paper looks at the possible role for skills mismatch in explaining this failure. The analysis is based on data from the IALS, an international skills survey conducted in 1994-98. Multiple choice models are...