OBJECTIVE With emergence and geographically expanding of antimalarial resistance worldwide, molecular markers are essential tool for surveillance of resistant Plasmodium parasites. Recently, single-nucleotide polymorphisms (SNPs) in the PF3D7_1343700 kelch propeller (K13-propeller) domain are shown to be associated with artemisinin (ART) resistance in vivo and in vitro. This study aims to inves...

Studia Linguistica Universitatis Iagellonicae Cracoviensis » 2022 Volume 139, Issue 4 Additional Remarks to SLing 137(1): 83–84 and 138(2): 75–78 A

MicroRNAs (miRNAs) have been frequently reported to be diagnostic biomarkers and prognostic factors for cancer. The aim of the present study was to evaluate the clinical significance of microRNA-139 (miRNA-139) in hepatocellular carcinoma (HCC). All 31 patients enrolled in the present study had received curative hepatectomy. The objective miRNA was determined using miRNA microarray. The miRNA-1...

Lutz Reichardt, Ortsnamenbuch des Ostalbkreises. (Veröffentlichungen der Kommission für geschichtliche Landeskunde in Baden-Württemberg, Bd. 139-140), 2 Bde., Stuttgart (Kohlhammer) 1999. 419 u. 402 S.

Hematopoiesis depends on a tightly controlled balance of selfrenewal, proliferation, cell death and differentiation. Although the disturbance of this equilibrium creates a predisposition to leukemogenesis, targeted manipulation or modulation can in turn lead to therapeutic advances. In addition to chromosomal aberrations and frequently mutated genes such as NPM1 and FLT3, dysregulation of micro...

INTRODUCTION Increasing evidence suggested that microRNAs (miRNAs) play a critical role in tumorigenesis. Decreased expression of miRNA-139-5p has been observed in various types of cancers. However, the biological function of miRNA-139-5p in non-small cell lung cancer (NSCLC) is still largely unknown. METHODS Quantitative real-time PCR (qRT-PCR) was used to explore the expression level of miR...