Background: The evolutionary conserved 18 glycosyl hydrolase family contains chitinases and chitinase like proteins that share amino acid sequence homology with true chitinases but lack enzymatic activity. The chitinase like protein YKL-40, encoded by the chitinase3-like 1 gene (CHI3L1), has been found to be either the cause or a biomarker for asthma. However, its pattern of expression with dis...

Numerous published studies have suggested that there is association between heme oxygenase-1 (HO-1) gene polymorphisms and coronary heart disease (CHD) or restenosis (RS) after percutaneous coronary intervention (PCI). This study aimed to clarify this association using a meta-analysis method. We used a systematic search for studies on the association of HO-1gene polymorphisms with CHD or RS in ...