OBJECTIVE To investigate metabolic changes in brain networks by deep brain stimulation (DBS) of the medial prefrontal cortex (mPFC), nucleus accumbens (NAcc) and dorsomedial thalamus (DM) using positron emission tomography (PET) in naïve rats. METHODS 43 male Wistar rats underwent stereotactic surgery and concentric bipolar platinum-iridium electrodes were bilaterally implanted into one of th...

Objective We investigated whether dual-time-point 18-Fluorodeoxyglucose (18FDG) positron emission tomography/computed tomography (PET/CT) could improve the positive predictive value for detecting advanced colorectal neoplasms (cancer, adenoma ≥10 mm or adenoma with high-grade dysplasia). Methods We retrospectively searched for consecutive patients with a known primary cancer, who had a colonic ...

Abstract Background and Aims Acute T-cell mediated rejection (TCMR) is associated with the recruitment of mononuclear leukocytes into renal transplant, which corresponds to core conventional Banff classification. The boosted metabolism these inflammatory cells can be assessed by positron emission tomography (PET) quantifying uptake 18F-fluorodeoxyglucose (18FDG). correlation biopsy-based versus...

Background: Brown fat is a metabolically active tissue which can take up the 18FDG tracer used in PET/CT scans, potentially leading to diagnostic uncertainty. Metabolically brown more prevalent children than adults with recent studies demonstrating an incidence of uptake 34%–40% cancer. The resultant uncertainty impact clinicians’ ability interpret scans pediatric oncology patients and has pote...

Over the past few years, nuclear medicine has undergone impressive growth with the development of positron emission tomography (PET), especially using 18Ffluoro-deoxy-glucose (18FDG), and new approaches in targeted radionuclide therapy. These developments pave the way for personalized medicine by offering practical solutions, especially in oncology, neurology, and cardiology. Novel radiopharmac...

Objetivo: presentar el caso clínico de un paciente con cáncer próstata metastásico quien presentó encefalitis anti-LGI1 (anti-proteína 1 inactivada del glioma rica en leucina), tratado inmunoglobulina, esteroides y docetaxel, obteniendo recuperación completa síntomas neurológicos. Presentación caso: 68 años antecedente adenocarcinoma Gleason 4+5 estadio IV por T3N1M1 (compromiso óseo costal met...