Vesicular release of neurotransmitter is the universal output signal of neurons in the brain. It is generally believed that fast transmitter release is restricted to nerve terminals that contact postsynaptic cells in the gray matter. Here we show in the rat brain that the neurotransmitter glutamate is also released at discrete sites along axons in white matter in the absence of neurons and nerv...

Patients undergoing oesophagectomy often have nutritional needs at the time of diagnosis and in the post-operative period. The aim of this article is to review the current literature and report on the author’s experience of routine feeding jejunostomy insertion following oesophagectomy. The records of forty-eight consecutive patients undergoing oesphagectomy under the author’s care were reviewe...

26 Actas Esp Psiquiatr 2009;37(6):320-325 cientes hiperfrecuentadores comparándolo con otro grupo de normofrecuentadores en tres centros de atención primaria. Método. La muestra está compuesta por 232 hiperfrecuentadores (definidos por un número de consultas igual o superior a 12 en el último año) y 93 normofrecuentadores. Los instrumentos utilizados son: un cuestionario de elaboración propia p...

Pregnancy increases the urinary excretion of chemicals in women and rodents. It is unknown whether the enhanced clearance of drugs during pregnancy involves changes in the expression of transporters that mediate chemical secretion and reabsorption. The purpose of this study was to quantify the mRNA and protein expression of efflux transporters in kidneys from virgin and pregnant mice on gestati...

The turbulence of a realistic dilute solution DNA macromolecules is investigated through hybrid Eulerian–Lagrangian approach that directly solves the incompressible Navier–Stokes equation alongside evolution 108 polymers, modelled as finitely extensible nonlinear elastic (FENE) dumbbells. At friction Reynolds number 320 and Weissenberg 2×104, drag reduction equal to 26%, which similar one obtai...

Private vegetable gardens are often contaminated with elevated levels of heavy metals (HM). Bioindication, using the visible symptoms developing in leaves, can provide simple, cost-effective and reliable detection of soil pollution. In this experiment five species of vegetables from different families were exposed to soil contaminated with HM dust given as copper / zinc / cadmium/ lead = 640 /3...

Objectives. We investigated whether amlodipine could improve angiogenic responses in a diabetic rat model of acute myocardial infarction (AMI) through improving bone marrow endothelial progenitor cell (EPC) mobilization, in the same way as angiotensin converting enzyme inhibitors. Methods. After induction of AMI by coronary artery ligation, diabetic rats were randomly assigned to receive perind...

The present study examined the effect of three methods of preparation on the properties and catalytic performance of Cu-Mn/SiO2 catalysts for the water gas shift reaction (WGSR). Impregnation and coprecipitation and the new approach of thermal decomposition of [Cu(H2O)6][Mn(dipic)2].2H2O/SiO2 inorganic precursor complex were used for the synthesis of the silica-supported copper-manganese mixed ...

AIMS We investigated whether the treatment with anthocyanins prevents the scopolamine-induced memory deficits and whether ectonucleotidase activities and purine levels are altered in the cerebral cortex (CC) and hippocampus (HC) in this model of mnemonic deficit in rats. MAIN METHODS The animals were divided into 4 experimental groups: control (vehicle), anthocyanins (Antho), scopolamine (SCO...

OBJECTIVE To study the impact of obesity on postoperative morbidity and outcome following surgical resection of primary oesophageal adenocarcinoma (EADC). METHODS From a prospective database, we compared clinicopathological findings (age, gender, surgical approach, tumour differentiation and stage), postoperative mortality, morbidity, length of hospitalisation, disease-free survival (DFS) and...