Vol. XLV (April 2008), 171–181 171 © 2008, American Marketing Association ISSN: 0022-2437 (print), 1547-7193 (electronic) *Alexander Chernev is Associate Professor of Marketing, Kellogg School of Management, Northwestern University (e-mail: ach@ northwestern.edu). The author thanks the anonymous JMR reviewers for their constructive comments. Ravi Dhar served as associate editor for this article...

BACKGROUND Alkylator resistance contributes to treatment failure in high-risk neuroblastoma. Buthionine sulfoximine (BSO) can deplete glutathione and synergistically enhance in vitro sensitivity to the alkylating agent melphalan (L-PAM) for many neuroblastoma cell lines, but optimal use of this combination needs to be defined because clinical responses have been less frequent and not durable. ...

A. A. Shanenko,1,2 M. D. Croitoru,3 and F. M. Peeters1 1TGM, Departement Fysica, Universiteit Antwerpen, Groenenborgerlaan 171, B-2020 Antwerpen, Belgium 2Bogoliubov Laboratory of Theoretical Physics, Joint Institute for Nuclear Research, 141980 Dubna, Russia 3EMAT, Departement Fysica, Universiteit Antwerpen, Groenenborgerlaan 171, B-2020 Antwerpen, Belgium Received 21 August 2006; published 16...

*Lilly Research Laboratories, Essener Bogen 7, D-22419 Hamburg, Germany; †Department of Pharmacology, University of Aarhus, DK-8000 Aarhus C, Denmark; ‡The Rolf Luft Center for Diabetes Research, Department of Molecular Medicine, Karolinska Institutet, SE-171 76 Stockholm, Sweden; §Department of Neuroscience, Karolinska Institutet, SE-171 77 Stockholm, Sweden; and ¶Center for Learning and Memor...

BACKGROUND This study was carried out to investigate the presence of irritable bowel syndrome (IBS) in college students and compare its distribution in the non-medical college and medical college students. METHODS We collected data from 508 students by inviting them to fill out a questionnaire based on Rome II criteria for the diagnosis of IBS from November 2001 to February 2004. Two major ci...

We have performed integral field spectroscopy of the radio galaxy 3C 171 (redshift z=0.238) with the TIGER instrument at the Canada France Hawaii telescope in the Hβ[OIII]4959-5007 wavelength region. We present the reconstructed Hβ and [OIII] images and compare them to the HST and radio maps. We discuss the variations of the [OIII]/Hβ line ratio throughout the nebulosity. We also analyze the ve...

The blowfly Calliphora has a preferred flight attitude from which it may transiently deviate either actively by voluntary aerobatics or, passively, by air turbulence. In order to regain its normal flight attitude the fly performs simultaneously a corrective flight manoeuvre and a compensatory head turn. This is made possible because Calliphora can turn its head about all 3 principal axes of its...

Carfilzomib [(2S)-N-[(S)-1-[(S)-4-methyl-1-[(R)-2-methyloxiran-2-yl]-1-oxopentan-2-ylcarbamoyl]-2-phenylethyl]-2-[(S)-2-(2-morpholinoacetamido)-4-phenylbutanamido]-4-methylpentanamide, also known as PR-171] is a selective, irreversible proteasome inhibitor that has shown encouraging results in clinical trials in multiple myeloma. In this study, the pharmacokinetics, pharmacodynamics, metabolism...

Division of Molecular Toxicology (R.A.M., M.O., M.I.-S.) and Unit of Genetic Toxicology (A.-K.A., A.R.), Institute of Environmental Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden, National Institute for Working Life, 171 84 Solna, Sweden (A.-K.A., A.R.), The Wallenberg Laboratory and Astra Draco AB, 221 00 Lund, Sweden (J.S.), and C 123 Riyadh Armed Forces Hospital, Riyadh 11159, Kin...