PURPOSE Radionuclide therapy is increasingly seen as a promising option to target minimal residual disease. Copper-67, scandium-47 and terbium-161 have a medium-energy β(-) emission which is similar to that of lutetium-177, but offer the advantage of having diagnostic partner isotopes suitable for pretreatment imaging. The aim of this study was to compare the efficacy of (67)Cu, (47)Sc and (161...

An independent validation was conducted of the Utah Autism and Developmental Disabilities Monitoring Network's (UT-ADDM) classification of children with autism spectrum disorder (ASD). UT-ADDM final case status (n = 90) was compared with final case status as determined by independent external expert reviewers (EERs). Inter-rater reliability (ICC = 0.84), specificity [0.83 (95 % CI 0.74-0.90)], ...

Revised selection mechanisms to medicine now include an adjunct admission test known as the HPAT. Stakeholder acceptability is a key issue. General Practitioners (GPs) represent an important stakeholder group. A questionnaire was administered to a regional sample of GPs evaluating their knowledge of the new selection system, views on acceptability, performance on sample HPAT questions and perce...

141 questionnaires were posted to GPs randomly selected in the Mid-West. 103 responses were received. 32 GPs (31%) strongly agreed and 65 GPs (63%) agreed that antibiotics are over used in general practice. 35 GPs (34%) felt under pressure to prescribe an antibiotic at least once a day. 41 GPs (40%) agreed that delayed prescriptions are a safe prescribing strategy. 53 GPs (51%) agreed that dela...

The American College of Medical Informatics (ACMI) periodically hosts a debate at the American Medical Informatics Association (AMIA) fall symposium on a timely topic in biomedical informatics. In 2014 a panel of ACMI fellows debated the following proposition: "The lack of interaction and collaboration between health IT vendors and academic clinical informatics units is stifling innovation and ...

Two clonally related Pseudomonas aeruginosa isolates, recovered from two patients admitted to a pediatric intensive care unit, were found to harbor a new OXA-2 variant (Asn148Asp), designated OXA-161. The plasmid location of bla(OXA-161) was demonstrated through electroporation to PAO1, and its codification in a class I integron (together with aacA4) was demonstrated through PCR and sequencing....

UNLABELLED Terbium offers 4 clinically interesting radioisotopes with complementary physical decay characteristics: (149)Tb, (152)Tb, (155)Tb, and (161)Tb. The identical chemical characteristics of these radioisotopes allow the preparation of radiopharmaceuticals with identical pharmacokinetics useful for PET ((152)Tb) and SPECT diagnosis ((155)Tb) and for α- ((149)Tb) and β(-)-particle ((161)T...

Romain Richard LIRMM UMR 5506 161 rue Ada CC 477 34095 Montpellier Cedex 5 France [email protected] Karen Godary-Dejean LIRMM UMR 5506 Université Montpellier 2 161 rue Ada CC 477 34095 Montpellier Cedex 5 France http://www.lirmm.fr/∼godary/ [email protected] Gregory Angles DEMAR Team, INRIA Université Montpellier 2 161 rue Ada CC 477 34095 Montpellier Cedex 5 France [email protected]

BACKGROUND The radiolanthanide (161)Tb has, in recent years, attracted increasing interest due to its favorable characteristics for medical application. (161)Tb exhibits similar properties to the widely-used therapeutic radionuclide (177)Lu. In contrast to (177)Lu, (161)Tb yields a significant number of short-ranging Auger/conversion electrons (≤50 keV) during its decay process. (161)Tb has bee...