Background. Currently available antithrombotic therapy for unstable angina is unwieldy and occasionally ineffective. This study was designed to investigate the potential of Hirulog, a new synthetic specific antithrombin agent, for the management of this condition. Methods and Results. A total of 55 patients in the acute phase of unstable angina received intravenous Hirulog according to one of t...

In the waters of Southern Baltic, off island Stora Ekön, lies wreck a ship lost in 1495 belonging to King John (Hans) Denmark (1455–1513). This paper draws on archaeological investigation site since 2013 and summarizes previous historical research. its design, construction, weapons technology is both rare example large carvel-built ‘great ship’ from final phase Middle Ages and, role as floating...

El presente artículo analiza las discusiones sobre relaciones entre episcopado y papado en tiempos del emperador Carlos V, a partir de la figura Juan Bernal Díaz Luco (1495-1556). inicio reforma protestante profundizó una serie debates el interior catolicismo respecto papel los obispos posibilidades intervención papal mismos. En este contexto difícil definición, escritos trayectoria muestran re...

We examined the pathway from grandparental childcare support at age 3 to child social and emotional outcomes 7 through maternal mental health mother–child relationship in a sample of n = 1495 biological mothers their children UK's Millennium Cohort Study. Structural equation modelling showed that time spent care grandparents was not associated with child's via psychological distress or conflict...