Norway spruce (Picea abies (L.) Karst.) seedlings growing in a growth pouch system were used to investigate the effects of the ectomycorrhizal fungus Hebeloma crustuliniforme (Bull. ex St. Amans) Quél. and various Cs/K ratios on the uptake of (134)Cs, expressed as a percentage of the total amount of (134)Cs supplied. The amount of (134)Cs taken up by seedlings increased with increasing Cs/K rat...

2-Aryl-substituted propionic acids, such as the important anti-inflammatory agent Naproxen, exist in two enantiomeric forms. The (S^-enantiomer of 2-(6-methoxynaphth-2-yl)propionic acid 1 is about 28 times more effective than the (/?)-enantiomer. A new catalytic method to synthesize Naproxen (S)-l involves the enantioselective decarboxylation of suitably substi­ tuted malonic acid derivatives. ...

The effects of a novel vasorelaxant agent, MCC-134 (1-[4-(1H-imidazol-1-yl)benzoyl]-N-methyl-cyclobutanecarbothioamide++ +), were examined on reconstituted ATP-sensitive K(+) (K(ATP)) channels, which are composed of an inwardly rectifying K(+) channel, Kir6.2, and three types of sulfonylurea receptors (SUR): SUR1, SUR2A, and SUR2B. Each type of K(ATP) channel was heterologously expressed in hum...

Significant progress has been made in the past year in developing new 'MHV' techniques for calculating multiparticle scattering amplitudes in Yang-Mills gauge theories. Most of the work so far has focussed on applications to Quantum Chromodynamics, both at tree and one-loop level. We show how such techniques can also be applied to abelian theories such as QED, by studying the simplest tree-leve...

Diabetes mellitus (DM) is a metabolic disease that is increasing worldwide. Furthermore, it is associated with the deregulation of vascular-related functions, which can develop into major complications among DM patients. Endothelial colony forming cells (ECFCs) have the potential to bring about medical repairs because of their post-natal angiogenic activities; however, such activities are impai...

BACKGROUND K-134 is a more potent antiplatelet drug with a selective inhibitory effect on phosphodiesterase 3 (PDE3) compared with its analogue, cilostazol. OBJECTIVES This study was performed to compare the ameliorating effects of K-134 and cilostazol on brain damage in an experimental photothrombotic cerebral infarction model. METHODS AND RESULTS We investigated the effects of oral preadm...

OBJECTIVES Kinetic characterization of TEM-134, a new TEM-type extended-spectrum beta-lactamase variant isolated from Citrobacter koseri during an Italian nationwide survey. TEM-134 is a natural derivative of TEM-2 with the following substitutions: E104K, R164H and G238S. METHODS Recombinant TEM-134 was purified from Escherichia coli HB101 (pMGP-134) by three chromatographic steps (cation-exc...