نتایج جستجو برای: 132
تعداد نتایج: 15936 فیلتر نتایج به سال:
Figure 1: (49 mm+10)x(2.2 words/mm)x(1 column) = 130 Figure 2: (65 mm+10)x(2.2 words/mm)x(2 column) = 330 Figure 3: (50 mm+10)x(2.2 words/mm)x(1 column) = 132 Figure 4: (50 mm+10)x(2.2 words/mm)x(1 column) = 132 Figure 5: (50 mm+10)x(2.2 words/mm)x(1 column) = 132 Figure 6a: (50 mm+10)x(2.2 words/mm)x(1 column) = 132 Figure 6b: (50 mm+10)x(2.2 words/mm)x(1 column) = 132 Figure 7: (61 mm+10)x(2....
OBJECTIVE The mechanisms underlying the pathogenesis of intractable epilepsy (IE) are still unclear. This study aimed to investigate the role of phosphorylation of Cyclase Response Element Binding Protein (p-CREB)/microRNA-132 (miR-132) signal pathway in the epileptogenesis. METHODS Temporal lobe epilepsy (TLE) was induced in rodents, and the brain tissues were collected. P-CREB expression wa...
Pathological growth of cardiomyocytes (hypertrophy) is a major determinant for the development of heart failure, one of the leading medical causes of mortality worldwide. Here we show that the microRNA (miRNA)-212/132 family regulates cardiac hypertrophy and autophagy in cardiomyocytes. Hypertrophic stimuli upregulate cardiomyocyte expression of miR-212 and miR-132, which are both necessary and...
We study the adsorption of a symmetric triblock copolymer of ethylene oxide, EO, and propylene oxide, PO, end-capped with quarternized poly(2-dimethylaminoethyl methacrylate), DMAEMA (DMAEMA(24)-EO(132)PO(50)EO(132)-DMAEMA(24)). Light scattering and tensiometry are used to measure the relative size of the associated structures and surface excess at the air-liquid interface. The adsorbed amount,...
The proteasome is a protein complex responsible for the degradation of polyubiquitin-tagged proteins. Besides the removal of target proteins, the proteasome also participates in the regulation of gene transcription in both proteolytic and non-proteolytic fashion. In this study the effect of proteasome inhibition on the basal expression of monocyte chemotactic protein-1 induced protein 1 (MCPIP1...
BACKGROUND Periodontitis is a chronic inflammatory disease induced by periodontopathogens such as Porphyromonas gingivalis (P. gingivalis). MicroRNAs (miRNAs) are small single-stranded noncoding RNAs that regulate gene expression at the level of translation. MiRNAs have been reported to be involved in inflammatory processes. In this study, we examined the effects of P. gingivalis-induced inflam...
Type 2 diabetes is characterized by hyperglycemia due to insulin resistance in the target tissue and insufficient insulin secretion from the beta cells. Finding new mechanisms and pathways involved in the regulation of insulin secretion from the pancreatic beta cells is of great importance. Our group has earlier found, miRNA-212 and miRNA-132 to be upregulated in the non-obese type 2 diabetic G...
A permutation is said to be alternating if it starts with rise and then descents and rises come in turn. In this paper we study the generating function for the number of alternating permutations on n letters that avoid or contain exactly once 132 and also avoid or contain exactly once an arbitrary pattern on k letters. In several interesting cases the generating function depends only on k and i...
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 117 1. Respiratory Effort Sensation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 118 1.1 Length-Tension Inappropriateness (LTI): A Unifying Paradigm f...
MicroRNAs (miRs) are important regulators of a wide range of biological processes. Antagomir studies suggest an implication of miR-132 in the functionality of the mammalian circadian clock. miR-212 and miR-132 are tandemly processed from the same transcript and share the same seed region. We found the clock modulator miR-132 and miR-212 to be expressed rhythmically in the central circadian cloc...
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