BACKGROUND Iodine 131 ablation following total thyroidectomy is considered an indispensable element of successful treatment of differentiated thyroid carcinoma (Dtc). because of the essential role of the kidneys in iodine clearance, (131)I therapy of Dtc in patients with end stage renal disease, particularly those maintained on haemodialysis, present a number of special features: the (131)I act...

The impact of radioiodine-131 ((131)I) treatment on thyroid cancer patients' quality of life is controversial. We conducted a cross-sectional study of 60 patients aged 18-73 years old who had recently underwent near total thyroidectomy due to papillary thyroid cancer and were scheduled for (131)I treatment. On admission to our department, prior to (131)I administration patients underwent clinic...

Pre-exposure prophylaxis (PrEP) is a well-established method for HIV prevention. Current guidelines suggest frequent screening & sexually transmitted infections (STI) of risk-populations – in high-income countries primarily men who have sex with (MSM) and subsequent PrEP-initiation. Since little known about Austrian PrEP-users, we initiated an observational cohort study to investigate behaviora...

A technic, efficient in use ~ of I TM, has been developed for introducing I TM into 4-mg. amounts of antibody or 3,-globulin protein at a level of 10 me. I ~al per mg. protein with a resulting iodine content of ~-S atoms per protein molecule of 160,000 molecular weight. Oak Ridge I TM was adjusted to pH 8 with borate buffer and the requisite amount of hydrochloric acid. To this solution was add...

The use of radioactive iodine ((131)I) for the treatment of thyroid carcinoma has changed over the past 50 y. These changes are based on increasing awareness of the biophysical properties of (131)I and new discoveries concerning the biology of iodine handling by thyroid cells. The therapeutic administration of (131)I for thyroid remnant ablation and for metastases requires an appreciation of io...

Whole body iodine-131 scan is a well-established imaging method for the detection of metastatic or residual tumor sites in patients with well-differentiated thyroid cancer. Many false-positive iodine-131 scan findings mimicking metastatic thyroid cancer have long been reported. The authors describe a false positive uptake in normal gallbladder on post-ablative iodine-131 scan in a patient with ...

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Detectable serum Tg levels associated with negative diagnostic (131)I whole body scan are not infrequently found in patients with differentiated thyroid cancer. Several researchers have shown that in these patients the administration of high (131)I activity (100 mCi or more) increases the sensitivity of a posttherapy diagnostic (131)I whole body scan performed a few days later and allows the de...

UNLABELLED In this study we compared whole body scintigraphy with Tc-99m-methoxyisobutylisonitrile (MIBI) and Iodine-131 NA (131I) for detection of residual and/or metastatic disease in well differentiated thyroid carcinoma. METHODS MIBI and I-131 scans were obtained in 60 patients. TSH measurements were done in all the patients prior to scintigraphy. RESULTS Out of 60 patients, for whom bo...

  This study was done in research institute of nuclear medicine from 1988-1992 for evaluation of the value of serum thyroglobulin level in comparison with 1-131 whole body scan (1-131 WBS) in patients with differentiated thyroid carcinoma. 204 patients who had total or near total thyroidectomy treated with 1-131 were evaluated in this study. Out of 204 patients 136 di...