Alpers-Huttenlocher syndrome (AHS), first described over 80 years ago is an autosomal recessive neurodegenerative disorder characterised by the triad of refractory seizures, neuro-developmental regression and hepatic failure. AHS is now known to be caused by mutations in the gene encoding the catalytic subunit of polymerase gamma (POLG1), an important mitochondrial DNA replication enzyme. The p...

Bacteriological failure with penicillin that has been used widely for years in group A beta hemolytic streptococcal (GABHS) tonsillopharyngitis is being reported as high as 30%. Because of this unresponsiveness, many different agents are being used as alternative options. We evaluated the effect of clarithromycin, amoxicillin/clavulanate (CAM), cefprozil and benzathine penicillin G (Pen G) on t...

OBJECTIVES To identify and quantify determinants of captan exposure among 74 private orchard pesticide applicators in the Agricultural Health Study (AHS). To adjust an algorithm used for estimating pesticide exposure intensity in the AHS based on these determinants and to compare the correlation of the adjusted and unadjusted algorithms with urinary captan metabolite levels. METHODS External ...

The Almahata Sitta (AhS) meteorite is a unique polymict ureilite. Recently, carbonaceous chondritic lithologies were identified in AhS. Organic matter (OM) ubiquitously found primitive chondrites. molecular and isotopic characteristics of this OM reflect its origin parent body processes, are particularly sensitive to heating. C1 AhS 671 91A investigated, focusing mainly on the OM. We that these...

PURPOSE Temporal lobe epilepsy (TLE) is often associated with Ammon's horn sclerosis (AHS) characterized by hippocampal cell death and dentate gyrus granule cell dispersion (GCD). Granule cells survive AHS and have been proposed to be hyperexcitable in TLE. Here we studied whether the passive excitability of granule cells correlates with the severity of AHS. METHODS We analyzed the passive me...

This paper considers a lane routing problem in an Automated Highway System (AHS). Lane routing is important because the problem of managing the traac ow on a multilane AHS plays a major role in an urban environment. On the other hand, because analytical approaches are impossible for various, almost unpredictable traac situations, traac simulations are indispensible for the design and the evalua...

The aim of this study is to demonstrate the growth-promoting effect of alginate hydrolysates (AHs) on the Manila clam Ruditapes philippinarum, and to verify the physiological change occurring within a living R. philippinarum stimulated by AHs. We show that growth of clams was dramatically promoted by supplementing a diet of the diatom Chaetoceros neogracile with AHs at 4 mg/mL. Furthermore, met...

Although asynchronous HTTP technologies have grown in importance with the emergence of Web 2.0, most web-based Adaptive Hypermedia Systems (AHS) still exclusively use serverside monitoring of user behaviour to set up the user model. This paper discusses how asynchronous technologies and client-side observation may lead to more accurate and detailed user models, and how that might benefit nextge...

The contents of this report reflect the views of the authors who are responsible for the facts and the accuracy of the data presented herein. The contents do not necessarily reflect the official views or policies of the State of California. EXECUTIVE SUMMARY The concept of automated highway system (AHS) was motivated primarily by its potential for large capacity and safety gains without requiri...

Anticonvulsant hypersensitivity syndrome (AHS) is a potentially fatal multiorgan drug reaction that presents with various cutaneous eruptions. There is a genetic predisposition to such reactions. We present a young woman with AHS due to carbamazepine that presented as an atypical erythema multiforme with elevated liver enzymes.