Melanoma is the deadliest form of skin cancer causing over 50,000 deaths annually worldwide. Immune checkpoint inhibitors (aCTLA4/aPD1) have improved melanoma survival, but many patients do not respond and face a high risk recurrence death. Tumor infiltrating lymphocytes (TILs) are heterogeneous population that play critical roles in response to aCTLA4/aPD1 remain incompletely characterized. Sp...

Women from all walks of life and age groups have been disproportionately affected by the covid pandemic—especially regarding financial security, mental health, additional care responsibilities.1234 It’s likely that female doctors are similarly affected. Over years more women than men presented to Practitioner Health, a confidential service for with illness.5 This gender gap has widened over pas...

LETHAL CUTANEOUS DISEASE IN TRANSGENIC MICE CONDITIONALLY EXPRESSING HTLV-I TAX* Hakju Kwon , Louise Ogle , Bobby Benitez , Jan Bohuslav , Mauricio Montano , Dean W. Felsher§ and Warner C. Greene From the Gladstone Institute of Virology and Immunology, San Francisco, CA 94158, the Departments of Medicine and of Microbiology and Immunology, University of California, San Francisco, California 941...

Red transparent single crystals of Ba9[NbN4]2O[CN2] were synthesised by the reaction of BaO coated Ba metal, C and Nb powder in arc-welded Nb ampoules at 1300 K. The title compound was characterised by X-ray single crystal diffraction (P1̄, a = 799.05(2), b = 962.61(2) and c = 1264.38(4) pm; α = 75.859(1), β = 85.745(1) and γ = 87.8621(8)◦; Z = 2) and Raman spectroscopy (νsym = 1234 and δ = 632/...

We present the techniques used to determine redshifts and to characterize the spectra of objects in the Caltech Faint Galaxy Redshift Survey in terms of spectral classes and redshift quality classes. These are then applied to spectra from an investigation of a complete sample of objects with Ks < 20 mag in a 2 by 7.3 arcmin 2 field at J005325+1234. Redshifts were successfully obtained for 163 o...

1 Departamento de Engenharia de Produção, Universidade Federal de Sao Carlos, C.P. 676, 13565-905, Sao Carlos, SP, Brazil [email protected]; [email protected] 2 Departamento de Matemática, Estat́ıstica e Computação, Universidade Estadual Paulista, C.P. 1234, 19060-400, Presidente Prudente, SP, Brazil [email protected] 3 Dept. of Technology and Operations Management, Univers...

ANALYSIS UNDER VENUS ATMOSPHERIC PRESSURE. S.M. Clegg, M.D. Dyar, S.K. Sharma, A.K. Misra, R.C. Wiens, S.E. Smrekar, S. Maurice and L. Esposito, Los Alamos National Laboratory, P.O. Box 1663 MS J565, Los Alamos, NM 87545, [email protected], Dept. of Astronomy, Mt. Holyoke College, South Hadley, MA 01075, Hawaii Institute of Geophysics and Planetology, University of Hawaii, 2525 Correa Rd., Honolu...

Let H be a 4-uniform hypergraph on an n-element vertex set V containing no 4-book of 3 pages, i.e., a hypergraph of 4 quadruples with vertices {1, 2, . . . , 7} and edges {1234, 1235, 1236, 4567}. Then for n>n0 e(H) ( n/2 2 )( n/2 2 ) . Moreover, here equality is possible only if V (H) can be partitioned into two sets A and B so that each quadruple of H intersects A (and B) in exactly two verti...

Well-shaped single crystals of binary AuSn2 were obtained as a side product during the synthesis of LiAu3Sn4. The structure of AuSn2 has been studied by X-ray diffractometer data: Pbca, Z = 8, a = 689.8(1), b = 701.1(1), c = 1177.3(2) pm, wR2 = 0.0533, 1234 F2 values, and 29 variables. The gold atoms show a distorted octahedral coordination by tin at Au–Sn distances ranging from 272 to 283 pm. ...

Weak Line Water Vapor Spectra in the Region 13 200–15 000 cm−1 Roland Schermaul,∗ Richard C. M. Learner,∗,1 A. A. D. Canas,† J. W. Brault,† Oleg L. Polyansky,‡,2 Djedjiga Belmiloud,‡ Nikolai F. Zobov,‡,2 and Jonathan Tennyson,‡,3 ∗Laser Optics & Spectroscopy, Blackett Laboratory, Imperial College of Science, Technology and Medicine, Prince Consort Road, London SW7 2BW, United Kingdom; †LASP (Sp...