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Purpose: General reduction of differential light sensitivity in glaucoma is a controversial issue. Purely diffuse visual field loss is not a sign of glaucoma, but it has been postulated that the best parts m the visual field are always affected to some extent. We studied the best parts of the visual field in a material of glaucomatow visual fields. Methods: Humphrey 30-2 threshold tests from 19...
Complement protein C3 is a 187-kDa (1641-aa) protein that plays a key role in complement activation and immune responses. Its hydrolyzed form, C3(H2O), is responsible for the initiation of the activation of alternative complement pathway. Previous analyses using mAbs, anilinonaphthalenesulfonate dyes, and functional studies have suggested that C3 is conformationally different from C3(H2O). We h...
BACKGROUND Several reports have suggested that propylthiouracil (PTU) may be safer than methimazole (MMI) for treating thyrotoxicosis during pregnancy because congenital malformations have been associated with the use of MMI during pregnancy. OBJECTIVES We investigated whether in utero exposure to antithyroid drugs resulted in a higher rate of major malformations than among the infants born t...
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