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تعداد نتایج: 695131 فیلتر نتایج به سال:
BACKGROUND Several rehabilitation programmes aim at reducing the impact of fatigue in MS patients. Acute and chronic fatigue should require different management. OBJECTIVES To assess the effects of individually tailored, multidisciplinary outpatient rehabilitation (MDR) on chronic fatigue. METHODS Forty-eight ambulatory MS patients with chronic fatigue were randomized to MDR or to MS-nurse ...
The isovolumetric relaxation time of the left ventricle (IRT) in 20 hypothyroid patients (133 +/- (SE of mean) 4 ms) was significantly longer than that in 23 normal subjects (95 +/- 3 ms). During a trial of thyroxine replacement the IRT in 12 hypothyroid patients fell from 143 +/- 4 ms to 107 +/- 4 ms. The IRT seems to be a useful index of end-organ function in hypothyroidism.
1 Principles and Instrumentation 3 1.1 Proteome and Proteomics 3 1.2 Need for Large-scale Analyses of Gene Products at the Protein Level 3 1.3 General Problems in Proteome Analyses 4 1.4 MS Instrumentation 5 1.4.1 Ionization Methods 6 1.4.2 Mass Analyzers 8 1.4.3 MS/MS 9 1.5 Methods of Sample Fractionation 10 1.5.1 2D-electrophoretic Separation of Complex Protein Mixtures 11 1.5.2 Liquid-phase ...
BACKGROUND Recently, the temporal excitable gap during atrial fibrillation (AF) has been identified as a vulnerable parameter for cardioversion of AF. In this study, we evaluated 5 methods to measure the refractory period (RP(AF)) and the excitable period (EP(AF)) during persistent AF. METHODS AND RESULTS In 11 goats instrumented with 83 epicardial atrial electrodes, persistent AF (43+/-34 da...
IMPORTANCE It remains unclear whether vitamin D insufficiency, which is common in individuals with multiple sclerosis (MS), has an adverse effect on MS outcomes. OBJECTIVES To determine whether serum concentrations of 25-hydroxyvitamin D (25[OH]D), a marker of vitamin D status, predict disease activity and prognosis in patients with a first event suggestive of MS (clinically isolated syndrome...
OBJECTIVE To assess whether parasite infection is correlated with a reduced number of exacerbations and altered immune reactivity in multiple sclerosis (MS). METHODS A prospective, double-cohort study was performed to assess the clinical course and radiological findings in 12 MS patients presenting associated eosinophilia. All patients presented parasitic infections with positive stool specim...
The objective of this study was to evaluate the biological activities and chemical fingerprint profiles extracts obtained from twelve Achillea L. species (A. lycaonica, A. biebersteinii (syn: arabica), kotschyi subsp. kotschyi, schischkinii, millefolium millefolium, sintenisii, setacea, teretifolia, wilhelmsii santolinoides wilhelmsii), nobilis, goniocephala, spinulifolia). antioxidant, enzyme ...
BACKGROUND Walking impairment has a major influence on the quality of life of people with multiple sclerosis (MS). The Multiple Sclerosis Walking Scale (MSWS-12) assesses the impact of MS on walking ability from the patient's perspective, but in its current form, is not amenable for use in many policy decision-making settings. OBJECTIVES Statistical 'mapping' methods were used to convert MSWS...
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