We investigated the effects of stathmin 1 (STMN1) silencing by small interfering (siRNA) on the sensitivity of esophageal cancer cells Eca-109 to paclitaxel. STMN1 siRNA was transiently transfected into Eca-109 cells. The effects of transfection were detected by quantitative polymerase chain reaction and western blotting. The effects of STMN1 silencing by siRNA on the sensitivity of esophageal ...

UNLABELLED Aims/Introduction:  Impaired fasting glucose (IFG) increases the risk of developing diabetes mellitus (DM). This study was carried out to characterize Japanese patients who have fasting glucose levels (FPG) between 100 and 109 mg/dL (IFG100-109). MATERIALS AND METHODS   A total of 1383 Japanese participants were examined by oral glucose tolerance test. We compared insulin secretory...

Sir, Hematopoiesis has been suggested to show a cyclic behavior under both normal and pathologic conditions,1-3 although other studies have not confirmed such a hypothesis.4,5 We report a peculiar case characterized by cyclic oscillations of neutrophils, monocytes and CD8+ lymphocytes in an asymptomatic subject. These findings suggest the existence of periodic hematopoiesis with a clinical expr...

BACKGROUND Autologous hematopoietic stem cell transplantation is considered the standard of care for younger patients with multiple myeloma. Several mobilization regimens are currently used, most commonly growth factors alone or in combination with chemotherapy. The aim of our study was to investigate the differences in lymphocyte subpopulation counts between three different mobilization regime...